RESEARCH NEWS 2012-07-23 Research News Today, Pfizer conceded that results of the first of four Phase 3 trials of intravenous bapineuzumab, a monoclonal antibody against Aβ, failed to meet its co-primary endpoints in some 1,100 patients with mild to moderate Alzheimer’s disease w
RESEARCH NEWS 2012-07-23 Research News Results of a nine-year longitudinal study indicate that women with the highest amounts of certain types of ceramide in their blood are more likely to develop Alzheimer’s disease. Researchers led by Michelle Mielke from the Mayo Clinic, Roche
Ludwig Maximilian UniversityMunich, Germany
PAPER Rutherford NJ, Dejesus-Hernandez M, Baker MC, Kryston TB, Brown PE, Lomen-Hoerth C, Boylan K, Wszolek ZK, Rademakers R
Neurology. 2012 Jul 31;79(5):482-3. PubMed: 22815561
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Lancet Neurol. 2012 Aug;11(8):697-707. PubMed: 22814541
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PAPER Hogel M, Laprairie RB, Denovan-Wright EM
PLoS One. 2012;7(7):e41152. PubMed: 22815947
PAPER Vlamings R, Benazzouz A, Chetrit J, Janssen ML, Kozan R, Visser-Vandewalle V, Steinbusch HW, von Hörsten S, Temel Y
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PAPER Reznichenko L, Cheng Q, Nizar K, Gratiy SL, Saisan PA, Rockenstein EM, González T, Patrick C, Spencer B, Desplats P, Dale AM, Devor A, Masliah E
J Neurosci. 2012 Jul 18;32(29):9992-8. PubMed: 22815513
PAPER Kambeitz JP, Bhattacharyya S, Kambeitz-Ilankovic LM, Valli I, Collier DA, McGuire P
Neurosci Biobehav Rev. 2012 Oct;36(9):2165-77. PubMed: 22813992
PAPER Oremus M, Tarride JE
Expert Rev Pharmacoecon Outcomes Res. 2012 Jun;12(3):275-7. PubMed: 22812550
PAPER Armstrong RA
Clin Exp Optom. 2012 Jul 19; PubMed: 22812926
PAPER Hamley IW
Chem Rev. 2012 Oct 10;112(10):5147-92. PubMed: 22813427
PAPER Ghosh T, Mustafa M, Kumar V, Datta SK, Bhatia MS, Sircar S, Banerjee BD
Asian J Psychiatr. 2012 Jun;5(2):160-3. PubMed: 22813660