Keys Found to KIBRA Memory Mystery

RESEARCH NEWS 2011-10-07 Research News KIBRA has been linked to human memory, but it hasn't been clear how this protein works in the brain. Two recent studies take steps to clarify its function in memory processes. One confirms that KIBRA supports episodic memory in humans,

PAPER Lomen-Hoerth C

Clinical phenomenology and neuroimaging correlates in ALS-FTD.

J Mol Neurosci. 2011 Nov;45(3):656-62. PubMed: 21971978

PAPER Mendoza-Garcés L, Mendoza-Rodríguez CA, Jiménez-Trejo F, Picazo O, Rodríguez MC, Cerbón M

Differential expression of estrogen receptors in two hippocampal regions during the estrous cycle of the rat.

Anat Rec (Hoboken). 2011 Nov;294(11):1913-9. PubMed: 21972199

PAPER Bortolato M, Shih JC

Behavioral outcomes of monoamine oxidase deficiency: preclinical and clinical evidence.

Int Rev Neurobiol. 2011;100:13-42. PubMed: 21971001

PAPER Röhnert P, Schröder UH, Ziabreva I, Täger M, Reymann KG, Striggow F

Insufficient endogenous redox buffer capacity may underlie neuronal vulnerability to cerebral ischemia and reperfusion.

J Neurosci Res. 2012 Jan;90(1):193-202. PubMed: 21971686

PAPER Elipenahli C, Stack C, Jainuddin S, Gerges M, Yang L, Starkov A, Beal MF, Dumont M

Behavioral Improvement after Chronic Administration of Coenzyme Q10 in P301S Transgenic Mice.

J Alzheimers Dis. 2012;28(1):173-82. PubMed: 21971408

PAPER Matsui Y, Satoh K, Miyazaki T, Shirabe S, Atarashi R, Mutsukura K, Satoh A, Kataoka Y, Nishida N

High sensitivity of an ELISA kit for detection of the gamma-isoform of 14-3-3 proteins: usefulness in laboratory diagnosis of human prion disease.

BMC Neurol. 2011;11:120. PubMed: 21970675

PAPER

Syncope with cholinesterase inhibitors.

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PAPER Andersen F, Viitanen M, Halvorsen DS, Straume B, Engstad TA

Co-morbidity and drug treatment in Alzheimer's disease. A cross sectional study of participants in the Dementia Study in Northern Norway.

BMC Geriatr. 2011;11:58. PubMed: 21970467

PAPER Zuliani G, Donnorso MP, Bosi C, Passaro A, Dalla Nora E, Zurlo A, Bonetti F, Mozzi AF, Cortese C

Plasma 24S-hydroxycholesterol levels in elderly subjects with late onset Alzheimer's disease or vascular dementia: a case-control study.

BMC Neurol. 2011;11:121. PubMed: 21970714

PAPER Naoi M, Maruyama W, Inaba-Hasegawa K, Akao Y

Type A monoamine oxidase regulates life and death of neurons in neurodegeneration and neuroprotection.

Int Rev Neurobiol. 2011;100:85-106. PubMed: 21971004

PAPER Weinreb O, Amit T, Bar-Am O, Youdim MB

A novel anti-Alzheimer's disease drug, ladostigil neuroprotective, multimodal brain-selective monoamine oxidase and cholinesterase inhibitor.

Int Rev Neurobiol. 2011;100:191-215. PubMed: 21971009

PAPER Van der Schyf CJ, Geldenhuys WJ

Multimodal drugs and their future for Alzheimer's and Parkinson's disease.

Int Rev Neurobiol. 2011;100:107-25. PubMed: 21971005

PAPER Wexler EM, Rosen E, Lu D, Osborn GE, Martin E, Raybould H, Geschwind DH

Genome-wide analysis of a Wnt1-regulated transcriptional network implicates neurodegenerative pathways.

Sci Signal. 2011 Oct 4;4(193):ra65. PubMed: 21971039

PAPER Jing F, Mogi M, Sakata A, Iwanami J, Tsukuda K, Ohshima K, Min LJ, Steckelings UM, Unger T, Dahlöf B, Horiuchi M

Direct stimulation of angiotensin II type 2 receptor enhances spatial memory.

J Cereb Blood Flow Metab. 2011 Oct 5; PubMed: 21971355