PAPER Ramos BP, Stark D, Verduzco L, van Dyck CH, Arnsten AF
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PAPER Franowicz JS, Arnsten AF
The alpha-2a noradrenergic agonist, guanfacine, improves delayed response performance in young adult rhesus monkeys.
Psychopharmacology (Berl). 1998 Mar;136(1):8-14. PubMed: 9537677PAPER Arnsten AF, Cai JX, Goldman-Rakic PS
The alpha-2 adrenergic agonist guanfacine improves memory in aged monkeys without sedative or hypotensive side effects: evidence for alpha-2 receptor subtypes.
J Neurosci. 1988 Nov;8(11):4287-98. PubMed: 2903226PAPER Kruggel F
MRI-based volumetry of head compartments: normative values of healthy adults.
Neuroimage. 2006 Mar;30(1):1-11. PubMed: 16289929PAPER Wang M, Gamo NJ, Yang Y, Jin LE, Wang XJ, Laubach M, Mazer JA, Lee D, Arnsten AF
Neuronal basis of age-related working memory decline.
Nature. 2011 Aug 11;476(7359):210-3. PubMed: 21796118PAPER Sherwood CC, Gordon AD, Allen JS, Phillips KA, Erwin JM, Hof PR, Hopkins WD
Aging of the cerebral cortex differs between humans and chimpanzees.
Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13029-34. PubMed: 21788499PAPER Kong J, Xu Z
Massive mitochondrial degeneration in motor neurons triggers the onset of amyotrophic lateral sclerosis in mice expressing a mutant SOD1.
J Neurosci. 1998 May 1;18(9):3241-50. PubMed: 9547233PAPER Park J, Kim Y, Choi S, Koh H, Lee SH, Kim JM, Chung J
Drosophila Porin/VDAC affects mitochondrial morphology.
PLoS One. 2010;5(10):e13151. PubMed: 20949033PAPER Campana WM
Schwann cells: activated peripheral glia and their role in neuropathic pain.
Brain Behav Immun. 2007 Jul;21(5):522-7. PubMed: 17321718PAPER Price RL, Lasek RJ, Katz MJ
Internal axonal cytoarchitecture is shaped locally by external compressive forces.
Brain Res. 1990 Oct 22;530(2):205-14. PubMed: 1702341ALS: Mutant Enzyme Does Not Hang Around, But Does Find Mitochondria
RESEARCH NEWS 2011-07-29 Research News Although it seems that many deficiencies can lead to amyotrophic lateral sclerosis, the enzyme superoxide dismutase 1 (SOD1) has long received the lion’s share of attention. Mutations in SOD1 cause disease in a subset of people with familial
Exercise and the Brain: More Support for Protective Effects
RESEARCH NEWS 2011-07-29 Research News Move your body, or else lose your mind? Two papers in this week’s Archives of Internal Medicine online support the idea that exercise can stave off cognitive decline. A five-year observational study led by Kristine Yaffe at the University of
What Primates Can Tell Us About Normal Brain Aging
RESEARCH NEWS 2011-07-29 Research News Human beings stand out from other species by having big brains, complex cognitive abilities, and long lifespans. Two new papers suggest we may pay for these blessings with increased vulnerability to age-related cognitive declines. Both studi
Paris: Renamed ARIA, Vasogenic Edema Common to Anti-Amyloid Therapy
CONFERENCE COVERAGE 2011-07-29 Conference Coverage After disappointing trial results for Alzheimer’s disease (AD) drugs, all eyes are on the Phase 3 clinical trials of two monoclonal antibodies to amyloid-β: bapineuzumab, developed by Janssen Alzheimer Immunotherapy and Pfizer, and sol
PAPER Larson EB
Brains and aging: Comment on "Physical activity and cognition in women with vascular conditions" and "Activity energy expenditure and incident cognitive impairment in older adults".
Arch Intern Med. 2011 Jul 25;171(14):1258-9. PubMed: 21771895Current Filters
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