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PAPER Nozaki K, Beal MF
Neuroprotective effects of L-kynurenine on hypoxia-ischemia and NMDA lesions in neonatal rats.
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J Neurol Sci. 1992 Mar;108(1):80-7. PubMed: 1385624Archna Bajaj on Meta-analysis of the relationship between Parkinson disease and melanoma.
COMMENT It was exciting to read the paper by Liu and colleagues, one for which I had been waiting. When researching the literature for the meta-analysis I wrote on PD and non-melanoma cancers (showing reduced cancer risk ratios with relative risk of 0.73 and a 95
PAPER Inzelberg R, Israeli-Korn SD
The particular relationship between Parkinson's disease and malignancy: a focus on skin cancers.
J Neural Transm. 2009 Nov;116(11):1503-7. PubMed: 19789839PAPER Ferreira JJ, Neutel D, Mestre T, Coelho M, Rosa MM, Rascol O, Sampaio C
Skin cancer and Parkinson's disease.
Mov Disord. 2010 Jan 30;25(2):139-48. PubMed: 20063399PAPER Fiala KH, Whetteckey J, Manyam BV
Malignant melanoma and levodopa in Parkinson's disease: causality or coincidence?
Parkinsonism Relat Disord. 2003 Aug;9(6):321-7. PubMed: 12853231PAPER Herrero Hernández E
Pigmentation genes link Parkinson's disease to melanoma, opening a window on both etiologies.
Med Hypotheses. 2009 Mar;72(3):280-4. PubMed: 19027242PAPER Bajaj A, Driver JA, Schernhammer ES
Parkinson's disease and cancer risk: a systematic review and meta-analysis.
Cancer Causes Control. 2010 May;21(5):697-707. PubMed: 20054708Archna Bajaj
Case Western Reserve UniversityCleveland, United States
PAPER Liu R, Gao X, Lu Y, Chen H
Meta-analysis of the relationship between Parkinson disease and melanoma.
Neurology. 2011 Jun 7;76(23):2002-9. PubMed: 21646627Sanjay Pimplikar on Intraneuronal APP, not free Aβ peptides in 3xTg-AD mice: implications for tau versus Aβ-mediated Alzheimer neurodegeneration.
COMMENT It is a healthy sign that the paper by Winton et al. has initiated a debate over intraneuronal Aβ, as more studies are appearing in the literature suggesting that intraneuronal Aβ could play a pathological role in Alzheimer’s disease (AD). This issue can
Iris Oren
UCL Insitute of NeurologyLondon
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