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Jeffrey L. Noebels on Hippocampal Storms Leave Lasting Marks

COMMENT Chronic hippocampal seizures impair cognition, an all-too-common biological comorbidity of temporal lobe epilepsy. What can be done? In the face of irreversible hippocampal cell loss followed by extensive structural rearrangements due to axonal sprouting, ...

Hippocampal Storms Leave Lasting Marks

RESEARCH NEWS 2017-10-20 Research News In Alzheimer’s disease, seizures in the hippocampus contribute to cognitive decline. Scientists have known for some time that this correlates with persistent loss of the calcium-binding protein calbindin-D28k, a regulator of synaptic ...

ALS Kin Have More Neuropsychiatric Disease

RESEARCH NEWS 2017-10-20 Research News ALS used to be thought of as a disease purely of the motor system, but more recently scientists have uncovered ties with frontotemporal dementia, and even certain neuropsychiatric diseases. Now, scientists led by Orla Hardiman, Beaumont ...

Andrew Neish

Emory University School of Medicine
Atlanta, United States

Microbiota from Wild Mice Protect Lab Mice from Disease

RESEARCH NEWS 2017-10-20 Research News In the confines of the animal room, lab mice reared for research encounter few microbes. While this safeguards against random infections and improves experimental reproducibility, the artificially sterile environment on its own may have ...

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