PAPER Tsvetkova D, Obreshkova D, Zheleva-Dimitrova D, Saso L
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331159 RESULTS
PAPER Andrieux K, Couvreur P
Nanomedicine as a promising approach for the treatment and diagnosis of brain diseases: the example of Alzheimer's disease.
Ann Pharm Fr. 2013 Jul;71(4):225-33. PubMed: 23835020PAPER Dartigues JF, Foubert-Samier A, Helmer C
[Relationship between educational level and dementia: Social factor and age-related chronic disease].
Rev Epidemiol Sante Publique. 2013 Aug;61 Suppl 3:S195-8. PubMed: 23835147PAPER Vossel KA, Beagle AJ, Rabinovici GD, Shu H, Lee SE, Naasan G, Hegde M, Cornes SB, Henry ML, Nelson AB, Seeley WW, Geschwind MD, Gorno-Tempini ML, Shih T, Kirsch HE, Garcia PA, Miller BL, Mucke L
Seizures and epileptiform activity in the early stages of Alzheimer disease.
JAMA Neurol. 2013 Sep 1;70(9):1158-66. PubMed: 23835471PAPER Kingwell K
Alzheimer disease: CSF levels of mitochondrial DNA-a new biomarker for preclinical Alzheimer disease?
Nat Rev Neurol. 2013 Aug;9(8):420. PubMed: 23835537PAPER Shulman JM, Chen K, Keenan BT, Chibnik LB, Fleisher A, Thiyyagura P, Roontiva A, McCabe C, Patsopoulos NA, Corneveaux JJ, Yu L, Huentelman MJ, Evans DA, Schneider JA, Reiman EM, De Jager PL, Bennett DA
Genetic susceptibility for Alzheimer disease neuritic plaque pathology.
JAMA Neurol. 2013 Sep 1;70(9):1150-7. PubMed: 23836404PAPER Almeida S, Gascon E, Tran H, Chou HJ, Gendron TF, Degroot S, Tapper AR, Sellier C, Charlet-Berguerand N, Karydas A, Seeley WW, Boxer AL, Petrucelli L, Miller BL, Gao FB
Modeling key pathological features of frontotemporal dementia with C9ORF72 repeat expansion in iPSC-derived human neurons.
Acta Neuropathol. 2013 Sep;126(3):385-99. PubMed: 23836290PAPER Byrne S, Heverin M, Elamin M, Bede P, Lynch C, Kenna K, Maclaughlin R, Walsh C, Al Chalabi A, Hardiman O
Aggregation of neurologic and neuropsychiatric disease in amyotrophic lateral sclerosis kindreds: A Population-Based Case-Control Cohort Study of Familial and Sporadic Amyotrophic Lateral Sclerosis.
Ann Neurol. 2013 Jul 9; PubMed: 23836460PAPER Dwivedi AK, Iyer PK
Therapeutic Strategies to Prevent Alzheimer's Disease Pathogenesis Using A Fluorescent Conjugated Polyelectrolyte.
Macromol Biosci. 2013 Jul 8; PubMed: 23836416PAPER Roohani P, Saha MK, Rosenbloom M
Creutzfeldt-Jakob Disease in the hospital setting: a case report and review.
Minn Med. 2013 May;96(5):46-9. PubMed: 23833837PAPER Lee JK, Shin JH, Hwang SG, Gwag BJ, McKee AC, Lee J, Kowall NW, Ryu H, Lim DS, Choi EJ
MST1 functions as a key modulator of neurodegeneration in a mouse model of ALS.
Proc Natl Acad Sci U S A. 2013 Jul 16;110(29):12066-71. PubMed: 23818595PAPER Chae JS, Gil Hwang S, Lim DS, Choi EJ
Thioredoxin-1 functions as a molecular switch regulating the oxidative stress-induced activation of MST1.
Free Radic Biol Med. 2012 Oct 17;53(12):2335-2343. PubMed: 23085515Tiina Kauppinen
University of ManitobaWinnipeg, Canada
Daniel Michaelson on Treatment with bexarotene, a compound that increases apolipoprotein-E, provides no cognitive benefit in mutant APP/PS1 mice.
COMMENT Since the introduction of a novel approach, such as the use of the RXR agonist bexarotene to counteract AD pathology, often brings controversy, it is important to identify consensus observations that ensue. A key finding from the Landreth group (Cramer et
Michel Goedert on Distinct α-synuclein strains differentially promote tau inclusions in neurons.
COMMENT This work demonstrates the existence of assembled α-synuclein strains, based on the cross-seeding (or not) of tau aggregation. This is important for understanding some human neurodegenerative diseases, where α-synuclein inclusions are present in different
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