183814 RESULTS

BI 409306

THERAPEUTICS Boehringer Ingelheim SUB 166499 Small Molecule Other Neurotransmitters Other Starting in 2011, Boehringer Ingelheim thus far has conducted 10 phase 1 studies testing both tablets and liquid formulations for this compound in about 500 people total in ...

Raj Hooli

Massachusetts General Hospital
Charlestown, United States

Ed Fila

Salt Lake City, United States

Two-in-One: Single Protein Untangles and Chops Up Tau Fibrils

RESEARCH NEWS 2015-10-07 Research News Aggregated proteins pose a challenge for the brain’s degradation machinery because these tangled clumps often conceal the cleavage sites necessary for proteolytic digestion. Cells first have to deploy specialized proteins called ...

S 38093

THERAPEUTICS Servier Small Molecule Other Neurotransmitters Between 2009 and 2015, four Phase 2 trials, testing doses ranging from 2 to 25 mg of S 38093 per day, have been conducted in a total of about 1,600 patients with mild to moderate Alzheimer's disease. Two ...

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