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A68: a major subunit of paired helical filaments and derivatized forms of normal Tau.
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Cell biology of the Alzheimer tangle.
Curr Opin Cell Biol. 1989 Feb;1(1):115-22. PubMed: 2517018Markus Zweckstetter
Max Planck Institute for Biophysical ChemistryGoettingen, Germany
PAPER OOSAWA F, Kasai M
A theory of linear and helical aggregations of macromolecules.
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Difference between the tau protein of Alzheimer paired helical filament core and normal tau revealed by epitope analysis of monoclonal antibodies 423 and 7.51.
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Tau proteins of Alzheimer paired helical filaments: abnormal phosphorylation of all six brain isoforms.
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Pathological proteins Tau 64 and 69 are specifically expressed in the somatodendritic domain of the degenerating cortical neurons during Alzheimer's disease. Demonstration with a panel of antibodies against Tau proteins.
Acta Neuropathol. 1990;80(2):111-7. PubMed: 2117840Does TauRx Drug Work by Oxidizing Tau?
RESEARCH NEWS 2013-02-21 Research News In 2008, Rember ™, aka methylene blue, created a stir when the drug’s sponsors reported that it slowed cognitive decline in a Phase 2 trial for Alzheimer’s disease, while other scientists questioned that interpretation (see ARF related news
PAPER Fernández E, García-Moreno JM, Pablos AM, Chacón J
May the Evaluation of Nitrosative Stress Through Selective Increase of 3-Nitrotyrosine Proteins Other Than Nitroalbumin and Dominant Tyrosine-125/136 Nitrosylation of Serum α-Synuclein Serve for Diagnosis of Sporadic Parkinson's Disease?
Antioxid Redox Signal. 2013 Mar 28; PubMed: 23418747PAPER Yeh HH, Young D, Gelovani JG, Robinson A, Davidson Y, Herholz K, Mann DM
Histone deacetylase class II and acetylated core histone immunohistochemistry in human brains with Huntington's disease.
Brain Res. 2013 Apr 4;1504:16-24. PubMed: 23419892PAPER Milanesi E, Bonvicini C, Alberici A, Pilotto A, Cattane N, Premi E, Gazzina S, Archetti S, Gasparotti R, Cancelli V, Gennarelli M, Padovani A, Borroni B
Molecular signature of disease onset in Granulin mutation carriers: a gene expression analysis study.
Neurobiol Aging. 2013 Jul;34(7):1837-45. PubMed: 23419701PAPER Maniwang E, Tayebi N, Sidransky E
Is Parkinson disease associated with lysosomal integral membrane protein type-2?: challenges in interpreting association data.
Mol Genet Metab. 2013 Apr;108(4):269-71. PubMed: 23419877Current Filters
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