PAPER Alberici A, Archetti S, Pilotto A, Premi E, Cosseddu M, Bianchetti A, Semeraro F, Salvetti M, Muiesan ML, Padovani A, Borroni B
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PAPER Forrester LT, Maayan N, Orrell M, Spector AE, Buchan LD, Soares-Weiser K
Aromatherapy for dementia.
Cochrane Database Syst Rev. 2014 Feb 25;2:CD003150. PubMed: 24569873PAPER Soukup SF, Verstreken P
PIWIL1 protein power targets tau therapy.
Nat Neurosci. 2014 Mar;17(3):334-5. PubMed: 24569826Divna Lazic
Serbia
Neurons Release Tau in Response to Excitation
RESEARCH NEWS 2014-02-27 Research News Numerous studies have reported that tau travels between neurons, but scientists are unsure how the protein exits the cell. In the February 17 Journal of Experimental Medicine, researchers led by David Holtzman at Washington University in St.
Kevin Keeker
New Funds to Hustle Drug Targets From Bench to Clinic
COMMUNITY NEWS 2014-02-27 Community News In an effort to close the gap between basic research and clinical drug development, several organizations have teamed up to create a new funding opportunity—the Dementia Consortium. Cambridge-based Alzheimer’s Research U.K. and London-based
PAPER Goedert M, Spillantini MG, Crowther RA
Cloning of a big tau microtubule-associated protein characteristic of the peripheral nervous system.
Proc Natl Acad Sci U S A. 1992 Mar 1;89(5):1983-7. PubMed: 1542696PAPER Georgieff IS, Liem RK, Couchie D, Mavilia C, Nunez J, Shelanski ML
Expression of high molecular weight tau in the central and peripheral nervous systems.
J Cell Sci. 1993 Jul;105 ( Pt 3):729-37. PubMed: 8408300PAPER Song Y, Mittendorf KF, Lu Z, Sanders CR
Impact of bilayer lipid composition on the structure and topology of the transmembrane amyloid precursor C99 protein.
J Am Chem Soc. 2014 Mar 19;136(11):4093-6. Epub 2014 Mar 11 PubMed: 24564538PAPER Acharya S, Safaie BM, Wongkongkathep P, Ivanova MI, Attar A, Klärner FG, Schrader T, Loo JA, Bitan G, Lapidus LJ
Molecular basis for preventing α-synuclein aggregation by a molecular tweezer.
J Biol Chem. 2014 Apr 11;289(15):10727-37. Epub 2014 Feb 24 PubMed: 24567327PAPER
Motor neuron disease: Intraspinal stem cell injections for ALS are safe and feasible.
Nat Rev Neurol. 2014 Mar;10(3) Epub 2014 Feb 25 PubMed: 24567005PAPER Meyer M, Gonzalez Deniselle MC, Hunt H, Kloet ER, De Nicola AF
The selective glucocorticoid receptor modulator CORT108297 restores faulty hippocampal parameters in Wobbler and corticosterone-treated mice.
J Steroid Biochem Mol Biol. 2014 Sep;143:40-8. Epub 2014 Feb 22 PubMed: 24565565PAPER Mitsumoto H, Factor-Litvak P, Andrews H, Goetz RR, Andrews L, Rabkin JG, McElhiney M, Nieves J, Santella RM, Murphy J, Hupf J, Singleton J, Merle D, Kilty M, Heitzman D, Bedlack RS, Miller RG, Katz JS, Forshew D, Barohn RJ, Sorenson EJ, Oskarsson B, Fernandes Filho JA, Kasarskis EJ, Lomen-Hoerth C, Mozaffar T, Rollins YD, Nations SP, Swenson AJ, Shefner JM, Andrews JA, Koczon-Jaremko BA, ALS COSMOS Study Group
ALS Multicenter Cohort Study of Oxidative Stress (ALS COSMOS): study methodology, recruitment, and baseline demographic and disease characteristics.
Amyotroph Lateral Scler Frontotemporal Degener. 2014 Jun;15(3-4):192-203. Epub 2014 Feb 24 PubMed: 24564738PAPER Cai W, Uribarri J, Zhu L, Chen X, Swamy S, Zhao Z, Grosjean F, Simonaro C, Kuchel GA, Schnaider-Beeri M, Woodward M, Striker GE, Vlassara H
Oral glycotoxins are a modifiable cause of dementia and the metabolic syndrome in mice and humans.
Proc Natl Acad Sci U S A. 2014 Apr 1;111(13):4940-5. Epub 2014 Feb 24 PubMed: 24567379Current Filters
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