COMMENT Zoe A. Klein and colleagues in Stephen Strittmatter's lab show that deficiency of TMEM106B partially rescues the lysosomal effects of knocking out progranulin (Grn) in mice. Klein et al. show that in Grn knockout mice, increased levels of lysosomal ...
PAPER Gachet Y, Codlin S, Hyams JS, Mole SE
btn1, the Schizosaccharomyces pombe homologue of the human Batten disease gene CLN3, regulates vacuole homeostasis.J Cell Sci. 2005 Dec 1;118(Pt 23):5525-36. Epub 2005 Nov 15 PubMed: 16291725
Humboldt State UniversityArcata, United States
University of ExeterExeter, United Kingdom
COMMENT This study is an important advance for CADASIL. CADASIL patients have no available therapies. They desperately need increased awareness of this terrible disease and an interest from researchers in developing disease-modifying drugs. Dr. Arboleda-Velazquez ...
CovanceWellesley, United States
Imago PharmaceuticalsJackson, United States
University of PadovaItaly
BRAIN Initiative: New Concepts and Early Stage Research for Large-Scale Recording and Modulation in the Nervous System (R21)
GRANT Friday, July 21, 2017- 16:15 National Eye Institute, National Center for Complementary and Integrative Health, National Institute on Aging, National Institute on Alcohol Abuse and Alcoholism, National Institute of Biomedical Imaging and Bioengineering, ...
Administrative Supplements for the U.S.-Japan Brain Research Cooperative Program (BRCP)-U.S. Entity (Admin Supplement)
GRANT Friday, July 21, 2017- 16:15 National Institute of Neurological Disorders and Stroke, National Center for Advancing Translational Sciences, National Center for Complementary and Integrative Health, National Institute on Aging, National Institute of ...
NIMH Administrative Supplement Program to Enable Continuity of Research Experiences of MD/PhDs during Clinical Training (Admin Supp)
GRANT Friday, July 21, 2017- 16:15 National Institute of Mental Health NIMH accepts and reviews applications on a continuous basis until April 1 of each fiscal year. Applications received after April 1 will be considered for funding in the next fiscal year. ...
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