PAPER Sanchez-Juan P, Hagen J, Henry M, Ghosh P, Gesierich B, Gorno-Tempini M, Miller BL, Jagust WJ, Rabinovici GD

PET PIB Utility in Clinical Practice: Learning from the Unexpected Findings.

Human Amyloid Imaging Abstract. 2012 Jan 1;

PAPER Rosario B, Bi W, Weissfeld L, Klunk W, Mathis C, Matan C, Berginc M, Price J

Evaluation of Voxel Concordance-Discordance Between [11C]PIB and Florbetapir PET Group Difference T-Maps for Amyloid(+) Vs. Amyloid(-) Subject Groups.

Human Amyloid Imaging Abstract. 2012 Jan 1;

PAPER Rieck J, Rodrigue K, Kennedy K, Hebrank A, Devous, Sr M, Park D

Elevated Beta-Amyloid Burden is Associated with Neural Differences in Face Processing in Healthy, Non-Demented Older Adults.

Human Amyloid Imaging Abstract. 2012 Jan 1;

PAPER Ossenkoppele R, Zwan M, Adriaanse S, Boellaard R, Windhorst A, Barkhof F, Lammertsma A, Scheltens P, van der Flier W, van Berckel B

Increased Parietal Amyloid Burden and Metabolic Dysfunction in Alzheimer’s Disease with Early Onset.

Human Amyloid Imaging Abstract. 2012 Jan 1;

PAPER Oh H, Mormino E, Jagust W

Effects of Age and Beta-Amyloid Deposition on Brain Activity and Functional Connectivity during Episodic Memory Encoding in Cognitively Normal Elderly.

Human Amyloid Imaging Abstract. 2012 Jan 1;

PAPER Marchant N, Reed B, Sanossian N, Madison C, Dhada R, Kriger S, DeCarli C, Weiner M, Chui H, Jagust W

Contribution of Vascular Brain Injury and Brain Abeta to Cognitive Function.

Human Amyloid Imaging Abstract. 2012 Jan 1;

PAPER Lehmann M, Ghosh P, Madison C, Corbetta C, Long A, Miller B, Jagust W, Rabinovici G

Diverging PIB and FDG Covariance Patterns Across Clinical Variants of AD.

Human Amyloid Imaging Abstract. 2012 Jan 1;

PAPER Cintron A, Rosen R, Ciliax B, Walker L, LeVine III H

PIB Binding in APP-Transgenic Mice Exogenously Seeded with AD-brain Extract.

Human Amyloid Imaging Abstract. 2012 Jan 1;

PAPER Amariglio R, Wadsworth L, Lorius N, Becker A, Johnson K, Sperling R, Rentz D

Subjective Cognitive Complaint Is Associated with Increased Amyloid Burden in Cognitively Normal Individuals.

Human Amyloid Imaging Abstract. 2012 Jan 1;

Beth Snitz

University of Pittsburgh
Pittsburgh, United States

Gary Landreth on ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models.

COMMENT Reply to comment by Jian-Ping Guo, P.L. McGeer, and Claudia Schwab We communicated the results of our study in advance of publication with these authors. It is important that oral administration of bexarotene employ the micronized form of the drug (Targre

James R. Connor on Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export.

COMMENT This paper by Lei et al. provides two important novel observations. Firstly, as a parkinsonian model, the tau knockout mice are exciting because they do not show symptoms of disease until 12 months of age; thus, similar to Parkinson’s patients, there is a

Wiep Scheper on Differential effects of unfolded protein response pathways on axon injury-induced death of retinal ganglion cells.

COMMENT In this paper, Hu and colleagues explore the role of the unfolded protein response (UPR) in neurodegeneration of retinal ganglion cells in the context of traumatic optic nerve injury and glaucoma. The data presented may indicate that selective activation

News Focus: 2012 Human Amyloid Imaging Conference

CONFERENCE COVERAGE 2012-02-24 Conference Coverage When 225 researchers from around the world convened in Miami to exchange the latest on β amyloid positron emission tomography (PET) on 12-13 January 2012, there was a palpable sense of urgency. At the 6th Annual Human Amyloid Imaging (

Peptide Sparks Synaptic Plasticity, Improves Memory in Rodents

RESEARCH NEWS 2012-02-24 Research News A small peptide called FGL boosts learning and memory when administered to rodents, and is poised to begin clinical trials in Alzheimer’s disease patients this year. Intriguingly, FGL sharpens memory in wild-type rats as well as in several d