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PAPER Forloni G, Iussich S, Awan T, Colombo L, Angeretti N, Girola L, Bertani I, Poli G, Caramelli M, Grazia Bruzzone M, Farina L, Limido L, Rossi G, Giaccone G, Ironside JW, Bugiani O, Salmona M, Tagliavini F

Tetracyclines affect prion infectivity.

Proc Natl Acad Sci U S A. 2002 Aug 6;99(16):10849-54. PubMed: 12149459

PAPER Axten JM, Medina JR, Feng Y, Shu A, Romeril SP, Grant SW, Li WH, Heerding DA, Minthorn E, Mencken T, Atkins C, Liu Q, Rabindran S, Kumar R, Hong X, Goetz A, Stanley T, Taylor JD, Sigethy SD, Tomberlin GH, Hassell AM, Kahler KM, Shewchuk LM, Gampe RT

Discovery of 7-methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a potent and selective first-in-class inhibitor of protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK).

J Med Chem. 2012 Aug 23;55(16):7193-207. PubMed: 22827572

Surprise Save: Excitability Protects Neurons from Lou Gehrig’s

RESEARCH NEWS 2013-10-11 Research News Some motor neurons succumb to the pathology of amyotrophic lateral sclerosis early in the disease, while others manage to survive much longer. In the October 2 Neuron, researchers suggest that the most vulnerable neurons are those that are l

Alzheimer’s Community Mobilizes to Show Benefits of Amyloid Scans

COMMUNITY NEWS 2013-10-11 Community News The Food and Drug Administration may have approved Eli Lilly and Company’s Amyvid, but insurers remain unconvinced that Aβ imaging will do patients much good. On September 27, the Centers for Medicare and Medicaid Services (CMS) formally is

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