Aβ 40, C-terminus

ANTIBODY monoclonal laboratory BAP-17<br />(Manfred Brockhaus, F. Hoffmann-La Roche Ltd., Basel,<br /><a href="http://www.ncbi.nlm.nih.gov/pubmed/9631452" target="_new">Paper</a>) immunogen = the peptide CMVGGVV conjugat

Aβ 42, C-terminus

ANTIBODY monoclonal laboratory BAP-15<br />(Manfred Brockhaus, F. Hoffmann-La Roche Ltd., Basel,<br /><a href="http://www.ncbi.nlm.nih.gov/pubmed/9631452" target="_new">Paper</a>)<br />Reference: <br /><a

Wai-Tong Chien on Editor’s Dozen: 13 Top AD Trends in 2010

COMMENT While scientists and researchers celebrate a number of revolutionary research findings and papers that advance our understanding of how genetics, and biological and risk factors contribute to Alzheimer's disease, more resources should be poured into

PAPER Brodaty H, Green A, Koschera A

Meta-analysis of psychosocial interventions for caregivers of people with dementia.

J Am Geriatr Soc. 2003 May;51(5):657-64. PubMed: 12752841

Zipping Zinc Portals Could Help Epilepsy, Possibly Alzheimer’s

RESEARCH NEWS 2011-01-12 Research News Epileptic seizures are bad for neurons, but does it come down to zinc ions to finish them off? That is the conclusion of a report in the January 5 Journal of Neuroscience. Researchers at Baylor College of Medicine, led by first author Jing Q

Clinical Trials: Task Force Supports Earlier Intervention

RESEARCH NEWS 2011-01-12 Research News Alzheimer’s disease has seen a disheartening string of failed clinical trials in recent years. While some experts see these failures as evidence of too little, too late, others argue that they have more to do with targets than with timing. E

PAPER Hirohata M, Ono K, Morinaga A, Ikeda T, Yamada M

Cerebrospinal fluid from patients with multiple system atrophy promotes in vitro α-synuclein fibril formation.

Neurosci Lett. 2011 Mar 10;491(1):48-52. PubMed: 21215793

PAPER Ohmi Y, Tajima O, Ohkawa Y, Yamauchi Y, Sugiura Y, Furukawa K

Gangliosides are essential in the protection of inflammation and neurodegeneration via maintenance of lipid rafts: elucidation by a series of ganglioside-deficient mutant mice.

J Neurochem. 2011 Mar;116(5):926-35. PubMed: 21214571

PAPER Tiwari M, Lopez-Cruzan M, Morgan WW, Herman B

Loss of caspase-2-dependent apoptosis induces autophagy after mitochondrial oxidative stress in primary cultures of young adult cortical neurons.

J Biol Chem. 2011 Mar 11;286(10):8493-506. PubMed: 21216964

PAPER Richards P, Didszun C, Campesan S, Simpson A, Horley B, Young KW, Glynn P, Cain K, Kyriacou CP, Giorgini F, Nicotera P

Dendritic spine loss and neurodegeneration is rescued by Rab11 in models of Huntington's disease.

Cell Death Differ. 2011 Feb;18(2):191-200. PubMed: 21217767

PAPER Maraldi T, Riccio M, Zambonin L, Vinceti M, De Pol A, Hakim G

Low levels of selenium compounds are selectively toxic for a human neuron cell line through ROS/RNS increase and apoptotic process activation.

Neurotoxicology. 2011 Mar;32(2):180-7. PubMed: 21215776

PAPER Flynn JM, Choi SW, Day NU, Gerencser AA, Hubbard A, Melov S

Impaired spare respiratory capacity in cortical synaptosomes from Sod2 null mice.

Free Radic Biol Med. 2011 Apr 1;50(7):866-73. PubMed: 21215798

PAPER Rostène W

[New prospects for chemokines].

Biol Aujourdhui. 2010;204(4):267-72. PubMed: 21215243

PAPER Goulburn AL, Alden D, Davis RP, Micallef SJ, Ng ES, Yu QC, Lim SM, Soh CL, Elliott DA, Hatzistavrou T, Bourke J, Watmuff B, Lang RJ, Haynes JM, Pouton CW, Giudice A, Trounson AO, Anderson SA, Stanley EG, Elefanty AG

A Targeted NKX2.1 Hesc Reporter Line Enables Identification of Human Basal Forebrain Derivatives.

Stem Cells. 2011 Jan 7; PubMed: 21218445

PAPER Kanellopoulos D, Gunning FM, Morimoto SS, Hoptman MJ, Murphy CF, Kelly RE, Glatt C, Lim KO, Alexopoulos GS

Hippocampal volumes and the brain-derived neurotrophic factor val66met polymorphism in geriatric major depression.

Am J Geriatr Psychiatry. 2011 Jan;19(1):13-22. PubMed: 21218562