PAPER L'Episcopo F, Tirolo C, Caniglia S, Testa N, Morale MC, Serapide MF, Pluchino S, Marchetti B
SEARCH RESULTS
331254 RESULTS
PAPER Accardi MV, Daniels BA, Brown PM, Fritschy JM, Tyagarajan SK, Bowie D
Mitochondrial reactive oxygen species regulate the strength of inhibitory GABA-mediated synaptic transmission.
Nat Commun. 2014;5:3168. PubMed: 24430741PAPER Gil-Mohapel J, Brocardo PS, Christie BR
The role of oxidative stress in Huntington's disease: are antioxidants good therapeutic candidates?
Curr Drug Targets. 2014 Apr;15(4):454-68. PubMed: 24428525PAPER Kurt TD, Bett C, Fernández-Borges N, Joshi-Barr S, Hornemann S, Rülicke T, Castilla J, Wüthrich K, Aguzzi A, Sigurdson CJ
Prion transmission prevented by modifying the β2-α2 loop structure of host PrPC.
J Neurosci. 2014 Jan 15;34(3):1022-7. PubMed: 24431459PAPER Mays CE, Kim C, Haldiman T, van der Merwe J, Lau A, Yang J, Grams J, Di Bari MA, Nonno R, Telling GC, Kong Q, Langeveld J, McKenzie D, Westaway D, Safar JG
Prion disease tempo determined by host-dependent substrate reduction.
J Clin Invest. 2014 Feb 3;124(2):847-58. Epub 2014 Jan 16 PubMed: 24430187PAPER Arenas E
Wnt signaling in midbrain dopaminergic neuron development and regenerative medicine for Parkinson's disease.
J Mol Cell Biol. 2014 Feb;6(1):42-53. Epub 2014 Jan 14 PubMed: 24431302PAPER Brashear A, Ozelius LJ, Sweadner KJ
ATP1A3 mutations: what is the phenotype?
Neurology. 2014 Feb 11;82(6):468-9. Epub 2014 Jan 15 PubMed: 24431297PAPER Pilleri M, Antonini A
Novel levodopa formulations in the treatment of Parkinson's disease.
Expert Rev Neurother. 2014 Feb;14(2):143-9. Epub 2014 Jan 13 PubMed: 24428803SNCA (α-synuclein)
ALZPEDIA Point mutations in the α-synuclein gene (SNCA), as well as duplication or triplication of wild-type SNCA, cause autosomal-dominant Parkinson’s disease. α-synuclein is abundantly expressed in the nervous system. In neurons, the protein is primarily localiz
2014 Budget Expands Alzheimer’s Funding
COMMUNITY NEWS 2014-01-17 Community News The 2014 U.S. budget, passed by Congress and signed into law by President Obama on January 16, contains some good news for Alzheimer’s researchers, with an additional $80 million earmarked to the National Institute on Aging, according to go
Parkinson's: Update on Gene Therapy, Fetal Cell Transplants
RESEARCH NEWS 2014-01-17 Research News Give a man a fish and you feed him for a day. Teach a man to fish and you feed him for a lifetime. Perhaps the saying could loosely apply to neurons in Parkinson's disease (PD). A pill supplements dopamine levels for a few hours. What i
PAPER Jarraya B, Boulet S, Ralph GS, Jan C, Bonvento G, Azzouz M, Miskin JE, Shin M, Delzescaux T, Drouot X, Hérard AS, Day DM, Brouillet E, Kingsman SM, Hantraye P, Mitrophanous KA, Mazarakis ND, Palfi S
Dopamine gene therapy for Parkinson's disease in a nonhuman primate without associated dyskinesia.
Sci Transl Med. 2009 Oct 14;1(2):2ra4. PubMed: 20368163PAPER Muramatsu S, Fujimoto K, Kato S, Mizukami H, Asari S, Ikeguchi K, Kawakami T, Urabe M, Kume A, Sato T, Watanabe E, Ozawa K, Nakano I
A phase I study of aromatic L-amino acid decarboxylase gene therapy for Parkinson's disease.
Mol Ther. 2010 Sep;18(9):1731-5. Epub 2010 Jul 6 PubMed: 20606642Jeffrey Jasper on Transcription Factor Nourishes Neuron-Muscle Pair in ALS Model
COMMENT This is an interesting manuscript. The authors demonstrated that transgenic overexpression of ATF3 in motor neurons of SOD1 mice promoted motor neuron survival and maintained axonal integrity and neuromuscular junction (NMJ) innervations. They found in AT
Transcription Factor Nourishes Neuron-Muscle Pair in ALS Model
RESEARCH NEWS 2014-01-17 Research News A gene that was once considered a simple cell stress marker turns out to be a short-term savior for motor neurons in a mouse model of amyotrophic lateral sclerosis. In the January 13 Proceedings of the National Academy of Sciences online, re
Current Filters
No filters selected