210591 RESULTS

Do Perivascular Macrophages Mediate Aβ Pathology?

RESEARCH NEWS 2017-05-26 Research News Amyloid-β is bad news for neurons, and also for the blood vessels that feed them. Now, a study from the lab of Costantino Iadecola, Weill Cornell Medical College in New York, proposes an unexpected role for perivascular macrophages (PVMs) as ...

DIAN-TU Fellowship Opportunity

JOB 2017-05-26 Employer Washington University School of Medicine Principal Investigator Randall Bateman Contact Description The DIAN-TU launched the first anti-amyloid Alzheimer’s prevention trials platform with two drugs and a third drug launching in ...

Certain Cancer Drugs Held Out as Prospects for ALS Therapy

RESEARCH NEWS 2017-05-26 Research News Could tyrosine kinase inhibitors, a standard tool of cancer treatment, help people with amyotrophic lateral sclerosis? Converging evidence suggests that this drug class may slow ALS progression, perhaps through multiple mechanisms. In the ...

PAPER Imamura K, Izumi Y, Watanabe A, Tsukita K, Woltjen K, Yamamoto T, Hotta A, Kondo T, Kitaoka S, Ohta A, Tanaka A, Watanabe D, Morita M, Takuma H, Tamaoka A, Kunath T, Wray S, Furuya H, Era T, Makioka K, Okamoto K, Fujisawa T, Nishitoh H, Homma K, Ichijo H, Julien JP, Obata N, Hosokawa M, Akiyama H, Kaneko S, Ayaki T, Ito H, Kaji R, Takahashi R, Yamanaka S, Inoue H

The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis.

Sci Transl Med. 2017 May 24;9(391) PubMed: 28539470

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