RESEARCH NEWS 2017-05-26 Research News Amyloid-β is bad news for neurons, and also for the blood vessels that feed them. Now, a study from the lab of Costantino Iadecola, Weill Cornell Medical College in New York, proposes an unexpected role for perivascular macrophages (PVMs) as ...
JOB 2017-05-26 Employer Washington University School of Medicine Principal Investigator Randall Bateman Contact firstname.lastname@example.org Description The DIAN-TU launched the first anti-amyloid Alzheimer’s prevention trials platform with two drugs and a third drug launching in ...
RESEARCH NEWS 2017-05-26 Research News Could tyrosine kinase inhibitors, a standard tool of cancer treatment, help people with amyotrophic lateral sclerosis? Converging evidence suggests that this drug class may slow ALS progression, perhaps through multiple mechanisms. In the ...
PAPER Wenqiang C, Lonskaya I, Hebron ML, Ibrahim Z, Olszewski RT, Neale JH, Moussa CE
Parkin-mediated reduction of nuclear and soluble TDP-43 reverses behavioral decline in symptomatic mice.Hum Mol Genet. 2014 Sep 15;23(18):4960-9. Epub 2014 May 8 PubMed: 24847002
PAPER Imamura K, Izumi Y, Watanabe A, Tsukita K, Woltjen K, Yamamoto T, Hotta A, Kondo T, Kitaoka S, Ohta A, Tanaka A, Watanabe D, Morita M, Takuma H, Tamaoka A, Kunath T, Wray S, Furuya H, Era T, Makioka K, Okamoto K, Fujisawa T, Nishitoh H, Homma K, Ichijo H, Julien JP, Obata N, Hosokawa M, Akiyama H, Kaneko S, Ayaki T, Ito H, Kaji R, Takahashi R, Yamanaka S, Inoue H28539470
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New York, United States
PAPER Bustos V, Pulina MV, Kelahmetoglu Y, Sinha SC, Gorelick FS, Flajolet M, Greengard P28533411
PAPER Bustos V, Pulina MV, Bispo A, Lam A, Flajolet M, Gorelick FS, Greengard P28533369
PAPER Jian C, Lu M, Zhang Z, Liu L, Li X, Huang F, Xu N, Qin L, Zhang Q, Zou D
miR-34a knockout attenuates cognitive deficits in APP/PS1 mice through inhibition of the amyloidogenic processing of APP.Life Sci. 2017 May 19; PubMed: 28533191
PAPER Tapias V, Hu X, Luk KC, Sanders LH, Lee VM, Timothy Greenamyre J
Synthetic alpha-synuclein fibrils cause mitochondrial impairment and selective dopamine neurodegeneration in part via iNOS-mediated nitric oxide production.Cell Mol Life Sci. 2017 May 22; PubMed: 28534083
PAPER Huang C, Zhu L, Li H, Shi FG, Wang GQ, Wei YZ, Liu J, Zhang F
Adulthood Exposure to Lipopolysaccharide Exacerbates the Neurotoxic and Inflammatory Effects of Rotenone in the Substantia Nigra.Front Mol Neurosci. 2017;10:131. Epub 2017 May 8 PubMed: 28533741
PAPER Larson ME, Greimel SJ, Amar F, LaCroix M, Boyle G, Sherman MA, Schley H, Miel C, Schneider JA, Kayed R, Benfenati F, Lee MK, Bennett DA, Lesné SE28533388
PAPER Das B, Rajagopalan S, Joshi GS, Xu L, Luo D, Andersen JK, Todi SV, Dutta AK
A novel iron (II) preferring dopamine agonist chelator D-607 significantly suppresses α-syn- and MPTP-induced toxicities in vivo.Neuropharmacology. 2017 May 19; PubMed: 28533164
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