UCLLondon, United Kingdom
The Dalles, United States
Medford, United States
RESEARCH NEWS 2017-02-25 Research News Wake up, sleepyhead—your risk of dementia may have just doubled. According to a study published February 22 in Neurology, people who slumber for more than nine hours per night have twice the risk of dementia as people who sleep for just six ...
PAPER Potvin O, Lorrain D, Forget H, Dubé M, Grenier S, Préville M, Hudon C22467987
PAPER Benito-León J, Bermejo-Pareja F, Vega S, Louis ED19473367
ViartisLongford Middlesex, United Kingdom
COMMENT The article represents a potentially interesting finding regarding the role of sTREM2 in triggering microglial activation. Although it is known that there is an increase in sTREM2 in many disease states, the role that sTREM2 plays is still relatively ...
COMMENT It was a pleasure to read this major and excellent paper that documents very elegantly the great potential of human PSCs for the development of better mouse models for AD. I did not expect the technique would be this powerful. This fascinating paper shows ...
RESEARCH NEWS 2017-02-25 Research News Mouse models of Alzheimer’s disease develop massive amyloidosis without losing many neurons, making them incomplete models of AD. In the February 23 Neuron, researchers led by Bart De Strooper and Pierre Vanderhaeghen at KU Leuven, Belgium, ...
COMMENT Zhong et al. report that soluble forms of TREM2 are able to elicit a robust proinflammatory response and promote survival in primary microglia. These findings provide a completely novel take on the biological roles of soluble TREM2. Previous work has ...
PAPER Westwood AJ, Beiser A, Jain N, Himali JJ, DeCarli C, Auerbach SH, Pase MP, Seshadri S28228567
Washington University School of MedicineSaint Louis, United States
PAPER Espuny-Camacho I, Arranz AM, Fiers M, Snellinx A, Ando K, Munck S, Bonnefont J, Lambot L, Corthout N, Omodho L, Eynden EV, Radaelli E, Tesseur I, Wray S, Ebneth A, Hardy J, Leroy K, Brion JP, Vanderhaeghen P, De Strooper B
PAPER Brion JP, Couck AM, Bruce M, Anderton B, Flament-Durand J1901750
No filters selected