PAPER Hochstrasser T, Ehrlich D, Marksteiner J, Sperner-Unterweger B, Humpel C

Matrix Metalloproteinase-2 and Epidermal Growth Factor are Decreased in Platelets of Alzheimer Patients.

Curr Alzheimer Res. 2011 Aug 30; PubMed: 21875409

PAPER Douglas Shytle R, Tan J, Bickford PC, Rezai-Zadeh K, Hou L, Zeng J, Sanberg PR, Sanberg CD, Alberte RS, Fink RC, Roschek B

Optimized Turmeric Extract Reduces β-Amyloid and Phosphorylated Tau Protein Burden in Alzheimer's Transgenic Mice.

Curr Alzheimer Res. 2011 Aug 30; PubMed: 21875408

PAPER Ceyhan E, Beg MF, Ceritoǧlu C, Wang L, Morris JC, Csernansky JG, Miller MI, Ratnanather JT

Metric Distances between Hippocampal Shapes Indicate Different Rates of Change Over Time in Nondemented and Demented Subjects.

Curr Alzheimer Res. 2011 Aug 30; PubMed: 21875412

PAPER Fodor KE, Pákáski M, Santha P, Janka Z, Kálmán J

[Cytoskeletal alterations in Alzheimer's disease: the "skeleton" of therapeutic hope?].

Neuropsychopharmacol Hung. 2011 Sep;13(3):163-71. PubMed: 21876225

Fernando Torres-Gil on Youth Group Promotes Alzheimer’s Research and Support for Elderly

COMMENT UGADA is an extraordinary youth group created to foster interest in aging among UCLA college students, and now one of our most active and accomplished student groups. They, in my opinion, represent a potential student movement that addresses the relevance

Fernando Torres-Gil

University of California, Los Angeles
United States

Breno Diniz on Synaptic autoregulation by metalloproteases and γ-secretase.

COMMENT Very interesting results from Restituito and colleagues. It is time to move forward and find out new alternatives to complement the classic amyloid cascade hypothesis of AD. 0 brenosatler

Michael Lardelli on More Than APP—γ-Secretase, Metalloproteases Control Neurotransmission

COMMENT The news article states that "γ-secretase appears primarily in endosomes," but the results of Area-Gomez et al. (Area-Gomez et al., 2009) do not support this. Most of the γ-secretase activity (at least in neurons) appears to be in the mitochondr

Xuping Li

�Houston Methodist Research Institute
Houston, United States

PAPER Takahashi H, Kirsch JR, Hashimoto K, London ED, Koehler RC, Traystman RJ

PPBP [4-phenyl-1-(4-phenylbutyl) piperidine] decreases brain injury after transient focal ischemia in rats.

Stroke. 1996 Nov;27(11):2120-3. PubMed: 8898825

PAPER Katnik C, Guerrero WR, Pennypacker KR, Herrera Y, Cuevas J

Sigma-1 receptor activation prevents intracellular calcium dysregulation in cortical neurons during in vitro ischemia.

J Pharmacol Exp Ther. 2006 Dec;319(3):1355-65. PubMed: 16988055

PAPER Hayashi T, Su TP

Sigma-1 receptor chaperones at the ER-mitochondrion interface regulate Ca(2+) signaling and cell survival.

Cell. 2007 Nov 2;131(3):596-610. PubMed: 17981125

PAPER Siddique T, Pericak-Vance MA, Brooks BR, Roos RP, Hung WY, Antel JP, Munsat TL, Phillips K, Warner K, Speer M

Linkage analysis in familial amyotrophic lateral sclerosis.

Neurology. 1989 Jul;39(7):919-25. PubMed: 2739919

Lisa Verges

MemoryCare
United States

Paper Alert: Do Blood-Borne Factors Control Brain Aging?

RESEARCH NEWS 2011-08-31 Research News Today in Nature, researchers led by Tony Wyss-Coray at Stanford University, Palo Alto, California, confirm what has been playfully called the “vampire principle”: Young blood rejuvenates older mice, while old blood contains factors that age