COMMENT This recent paper by Lui and colleagues provides valuable insight into how progranulin deficiency causes neurodegenerative disease. This study shows that progranulin deficiency causes activation of microglia and that the complement system is at least ...
RESEARCH NEWS 2016-05-05 Research News Like overzealous gardeners, microglia have been found to cut back synapses in mouse models of Alzheimer’s and Huntington’s disease. Now, researchers led by Eric Huang at the University of California, San Francisco, report that a similar ...
PAPER Farfel-Becker T, Vitner EB, Pressey SN, Eilam R, Cooper JD, Futerman AH
Spatial and temporal correlation between neuron loss and neuroinflammation in a mouse model of neuronopathic Gaucher disease.Hum Mol Genet. 2011 Apr 1;20(7):1375-86. Epub 2011 Jan 20 PubMed: 21252206
PAPER Yamada A, Saji M, Ukita Y, Shinoda Y, Taniguchi M, Higaki K, Ninomiya H, Ohno K
Progressive neuronal loss in the ventral posterior lateral and medial nuclei of thalamus in Niemann-Pick disease type C mouse brain.Brain Dev. 2001 Aug;23(5):288-97. PubMed: 11504598
PAPER Liszewski MK, Kolev M, Le Friec G, Leung M, Bertram PG, Fara AF, Subias M, Pickering MC, Drouet C, Meri S, Arstila TP, Pekkarinen PT, Ma M, Cope A, Reinheckel T, Rodriguez de Cordoba S, Afzali B, Atkinson JP, Kemper C
Intracellular complement activation sustains T cell homeostasis and mediates effector differentiation.Immunity. 2013 Dec 12;39(6):1143-57. Epub 2013 Dec 5 PubMed: 24315997
JOB 2016-05-05 Employer Macquarie University Principal Investigator Adam Walker Contact General Recruitment Enquiries: Daniella Oreskovic Description The Department of Biomedical Sciences in the Faculty of Medicine and Health Sciences is seeking a postdoctoral research ...
PAPER Campbell S, Manthorpe J, Samsi K, Abley C, Robinson L, Watts S, Bond J, Keady J27131277
PAPER McGuire LI, Poleggi A, Poggiolini I, Suardi S, Grznarova K, Shi S, de Vil B, Sarros S, Satoh K, Cheng K, Cramm M, Fairfoul G, Schmitz M, Zerr I, Cras P, Equestre M, Tagliavini F, Atarashi R, Knox D, Collins S, Haïk S, Parchi P, Pocchiari M, Green A27130376
PAPER Simuni T, Caspell-Garcia C, Coffey C, Lasch S, Tanner C, Marek K, PPMI Investigators27132498
PAPER Borgemeester RW, Lees AJ, van Laar T27132157
PAPER Shen T, Pu J, Si X, Ye R, Zhang B
An update on potential therapeutic strategies of Parkinson's disease based on pathogenic mechanisms.Expert Rev Neurother. 2016 May 3; PubMed: 27138872
PAPER Köhler CA, Magalhães TF, Oliveira JM, Alves GS, Knöchel C, Oertel-Knöchel V, Pantel J, Carvalho AF
Neuropsychiatric Disturbances in Mild Cognitive Impairment (MCI): a Systematic Review of Population-Based Studies.Curr Alzheimer Res. 2016 May 2; PubMed: 27137220
PAPER Matura S, Carvalho AF, Alves GS, Pantel J
Physical exercise for the treatment of neuropsychiatric disturbances in Alzheimer's dementia: possible mechanisms, current evidence and future directions.Curr Alzheimer Res. 2016 May 2; PubMed: 27137219
PAPER Zeng LL, Xie L, Shen H, Luo Z, Fang P, Hou Y, Tang B, Wu T, Hu D
Differentiating Patients with Parkinson's Disease from Normal Controls Using Gray Matter in the Cerebellum.Cerebellum. 2016 May 2; PubMed: 27138531
PAPER Lauritzen I, Pardossi-Piquard R, Bourgeois A, Pagnotta S, Biferi MG, Barkats M, Lacor P, Klein W, Bauer C, Checler F
Intraneuronal aggregation of the β-CTF fragment of APP (C99) induces Aβ-independent lysosomal-autophagic pathology.Acta Neuropathol. 2016 Apr 30; PubMed: 27138984
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