PAPER Balmaceda V, Cuchillo-Ibáñez I, Pujadas L, García-Ayllón MS, Saura CA, Nimpf J, Soriano E, Sáez-Valero J
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PAPER Yu Y, Logovinsky V, Schuck E, Kaplow J, Chang MK, Miyagawa T, Wong N, Ferry J
Safety, tolerability, pharmacokinetics, and pharmacodynamics of the novel γ-secretase modulator, E2212, in healthy human subjects.
J Clin Pharmacol. 2013 Dec 17; PubMed: 24343761PAPER Chen CY, Liao YF, Chang MY, Hu MK
Difluorophenylglycinols as new modulators of proteolytic processing of amyloid precursor proteins.
Arch Pharm (Weinheim). 2014 Mar;347(3):161-73. Epub 2013 Dec 11 PubMed: 24339192PAPER Acx H, Chávez-Gutiérrez L, Serneels L, Lismont S, Benurwar M, Elad N, De Strooper B
Signature amyloid β profiles are produced by different γ-secretase complexes.
J Biol Chem. 2014 Feb 14;289(7):4346-55. Epub 2013 Dec 13 PubMed: 24338474PAPER Yun HM, Kim HS, Park KR, Shin JM, Kang AR, il Lee K, Song S, Kim YB, Han SB, Chung HM, Hong JT
Placenta-derived mesenchymal stem cells improve memory dysfunction in an Aβ1-42-infused mouse model of Alzheimer's disease.
Cell Death Dis. 2013 Dec 12;4:e958. PubMed: 24336078PAPER Li B, Yu D, Xu Z
Activated protein C inhibits amyloid β production via promoting expression of ADAM-10.
Brain Res. 2014 Jan 30;1545:35-44. Epub 2013 Dec 12 PubMed: 24333930PAPER Macias MP, Gonzales AM, Siniard AL, Walker AW, Corneveaux JJ, Huentelman MJ, Sabbagh MN, Decourt B
A cellular model of amyloid precursor protein processing and amyloid-β peptide production.
J Neurosci Methods. 2014 Feb 15;223:114-22. Epub 2013 Dec 12 PubMed: 24333289PAPER Joshi YB, Giannopoulos PF, Chu J, Praticò D
Modulation of lipopolysaccharide-induced memory insult, γ-secretase, and neuroinflammation in triple transgenic mice by 5-lipoxygenase.
Neurobiol Aging. 2014 May;35(5):1024-31. Epub 2013 Nov 22 PubMed: 24332986PAPER Cheng X, He P, Lee T, Yao H, Li R, Shen Y
High activities of BACE1 in brains with mild cognitive impairment.
Am J Pathol. 2014 Jan;184(1):141-7. PubMed: 24332014PAPER Olsson B, Legros L, Guilhot F, Strömberg K, Smith J, Livesey FJ, Wilson DH, Zetterberg H, Blennow K
Imatinib treatment and Aβ42 in humans.
Alzheimers Dement. 2013 Dec 10; PubMed: 24331439PAPER Baptista FI, Henriques AG, Silva AM, Wiltfang J, da Cruz e Silva OA
Flavonoids as therapeutic compounds targeting key proteins involved in Alzheimer's disease.
ACS Chem Neurosci. 2014 Feb 19;5(2):83-92. Epub 2014 Jan 3 PubMed: 24328060PAPER Lopes P, Dyrnesli H, Lorenzen N, Otzen D, Ferapontova EE
Electrochemical analysis of the fibrillation of Parkinson's disease α-synuclein.
Analyst. 2014 Feb 21;139(4):749-56. PubMed: 24343298PAPER Fellner L, Wenning GK, Stefanova N
Models of Multiple System Atrophy.
Curr Top Behav Neurosci. 2013 Dec 14; PubMed: 24338664PAPER Dikiy I, Eliezer D
N-terminal acetylation stabilizes N-terminal helicity in lipid- and micelle-bound α-synuclein and increases its affinity for physiological membranes.
J Biol Chem. 2014 Feb 7;289(6):3652-65. Epub 2013 Dec 12 PubMed: 24338013PAPER Tsunemi T, Krainc D
Zn²⁺ dyshomeostasis caused by loss of ATP13A2/PARK9 leads to lysosomal dysfunction and alpha-synuclein accumulation.
Hum Mol Genet. 2014 Jun 1;23(11):2791-801. Epub 2013 Dec 13 PubMed: 24334770Current Filters
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