PAPER Hopkins PC

Neurodegeneration in a Drosophila model for the function of TMCC2, an amyloid protein precursor-interacting and apolipoprotein E-binding protein.

PLoS One. 2013;8(2):e55810. PubMed: 23409049

PAPER Mold M, Ouro-Gnao L, Wieckowski BM, Exley C

Copper prevents amyloid-β(1-42) from forming amyloid fibrils under near-physiological conditions in vitro.

Sci Rep. 2013;3:1256. PubMed: 23409247

PAPER Zhang M, Hausmann L, Song W

Targeting nascent soluble Aβ42 for potential Alzheimer drug development.

J Neurochem. 2013 May;125(3):329-31. PubMed: 23405973

PAPER Zivković L, Spremo-Potparević B, Siedlak SL, Perry G, Plećaš-Solarović B, Milićević Z, Bajić VP

DNA Damage in Alzheimer Disease Lymphocytes and Its Relation to Premature Centromere Division.

Neurodegener Dis. 2013 Feb 13; PubMed: 23406622

PAPER Schmidt C, Artjomova S, Hoeschel M, Zerr I

CSF prion protein concentration and cognition in patients with Alzheimer disease.

Prion. 2013 Feb 13;7(3) PubMed: 23406922

PAPER Arrighi HM, Gélinas I, McLaughlin TP, Buchanan J, Gauthier S

Longitudinal changes in functional disability in Alzheimer's disease patients.

Int Psychogeriatr. 2013 Jun;25(6):929-37. PubMed: 23406898

PAPER Koss DJ, Drever BD, Stoppelkamp S, Riedel G, Platt B

Age-dependent changes in hippocampal synaptic transmission and plasticity in the PLB1(Triple) Alzheimer mouse.

Cell Mol Life Sci. 2013 Feb 14; PubMed: 23407662

PAPER Tsuang D, Leverenz JB, Lopez OL, Hamilton RL, Bennett DA, Schneider JA, Buchman AS, Larson EB, Crane PK, Kaye JA, Kramer P, Woltjer R, Trojanowski JQ, Weintraub D, Chen-Plotkin AS, Irwin DJ, Rick J, Schellenberg GD, Watson GS, Kukull W, Nelson PT, Jicha GA, Neltner JH, Galasko D, Masliah E, Quinn JF, Chung KA, Yearout D, Mata IF, Wan JY, Edwards KL, Montine TJ, Zabetian CP

APOE ε4 increases risk for dementia in pure synucleinopathies.

JAMA Neurol. 2013 Feb;70(2):223-8. PubMed: 23407718

PAPER Haines JL

The importance of rare DNA variation in neurologic disease: cautionary tale.

Neurology. 2013 Mar 12;80(11):974-5. PubMed: 23408868

PAPER Toledo JB, Da X, Bhatt P, Wolk DA, Arnold SE, Shaw LM, Trojanowski JQ, Davatzikos C,

Relationship between plasma analytes and SPARE-AD defined brain atrophy patterns in ADNI.

PLoS One. 2013;8(2):e55531. PubMed: 23408997

PAPER Mori T, Koyama N, Guillot-Sestier MV, Tan J, Town T

Ferulic acid is a nutraceutical β-secretase modulator that improves behavioral impairment and alzheimer-like pathology in transgenic mice.

PLoS One. 2013;8(2):e55774. PubMed: 23409038

PAPER Sandebring A, Welander H, Winblad B, Graff C, Tjernberg LO

The pathogenic aβ43 is enriched in familial and sporadic Alzheimer disease.

PLoS One. 2013;8(2):e55847. Epub 2013 Feb 11 PubMed: 23409063

Edwin J. Weeber on Does Estrogen Put the Brakes on Aging in ApoE4-Positive Cells?

COMMENT The elegant study by Rasgon and colleagues identifies yet another unknown consequence of ApoE4 expression: increased telomere (TL) shortening. Furthermore, this study suggests that hormone replacement therapy (HT) can effectively counteract these changes

PAPER Sayed Y, Taxel P

The use of estrogen therapy in men.

Curr Opin Pharmacol. 2003 Dec;3(6):650-4. PubMed: 14644018

Mark Mattson on Does Estrogen Put the Brakes on Aging in ApoE4-Positive Cells?

COMMENT There has been a flurry of articles published within the past few years in which relatively shorter telomere length in lymphocytes has been associated with aging and numerous chronic diseases. A common factor in these conditions is that there is elevated