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Alpha-synuclein overexpression in PC12 and chromaffin cells impairs catecholamine release by interfering with a late step in exocytosis.

J Neurosci. 2006 Nov 15;26(46):11915-22. PubMed: 17108165

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Increased striatal dopamine release and hyperdopaminergic-like behaviour in mice lacking both alpha-synuclein and gamma-synuclein.

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Robert Edwards

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United States

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A pathologic cascade leading to synaptic dysfunction in alpha-synuclein-induced neurodegeneration.

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Genetic variability in the SNCA gene influences alpha-synuclein levels in the blood and brain.

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Abhinav Kumar

IIT Roorkee
Roorkee, India

Xuekai Zhang

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