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PLoS One. 2013;8(1):e52982. Epub 2013 Jan 3 PubMed: 23301011Hugo Geerts on TREM2 Mystery: Altered Microglia, No Effect on Plaques
COMMENT Our surprise reaction at this result might have been driven by our amyloid-centric view of Alzheimer’s disease. Effects on amyloid phagocytosis might not be the primary process driving vulnerability to certain TREM2 SNPs. TREM2 does other things besides a
Anouk Leeijen
Eckhard Mandelkow
DZNE (German Center for Neurodegenerative Diseases)Bonn, Germany
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