COMMENT With the failure of the semagacestat trials, it is easy to quickly dismiss γ-secretase as a viable drug target and move forward to alternative targets for the treatment of Alzheimer’s disease. However, in this letter to Cell, Bart De Strooper provides a ...
Other Released to theaters in January of 2015, the movie “Still Alice” tells the story of 50 year-old Alice Howland, a college professor who is diagnosed with early-onset Alzheimer’s disease. Based on the book of the same name by Lisa Genova (see Alzforum ...
GRANT Thursday, January 29, 2015- 08:15 National Institutes of Health: National Institute of Nursing Research (NINR) and National Institute on Aging (NIA) Money, property, or both to carry out an approved project or activity. The number of awards is contingent ...
GRANT Thursday, January 29, 2015- 08:00 National Institutes of Health: National Institute of Nursing Research (NINR) and National Institute on Aging (NIA) Up to $275,000 over two years. No more than $200,000 in direct costs may be requested in any single year. ...
RESEARCH NEWS 2015-01-29 Research News Clinicians can now choose between three approved PET Aβ imaging tracers: Eli Lilly’s florbetapir (Amyvid), GE Healthcare’s flutemetamol (Vizamyl), and Piramal Imaging’s florbetaben (Neuraceq). Are there significant differences in their ...
COMMUNITY NEWS 2015-01-29 Community News An easy word escapes her mid-lecture. Then she loses her way jogging familiar campus roads. These and other unsettling memory lapses prompt 50-year-old Alice Howland, a vivacious linguistics professor at the height of her career, to consult ...
PAPER Cabral C, Morgado PM, Campos Costa D, Silveira M, For the Alzheimer׳s Disease Neuroimaging Initiative25625698
Dementia: Improved decision tree aids differentiation of atypical Alzheimer disease from Creutzfeld-Jakob disease.Nat Rev Neurol. 2015 Jan 27; PubMed: 25623796
PAPER Mather KA, Armstrong NJ, Wen W, Kwok JB, Assareh AA, Thalamuthu A, Reppermund S, Duesing K, Wright MJ, Ames D, Trollor JN, Brodaty H, Schofield PR, Sachdev PS25625606
PAPER Nordberg A25623789
PAPER Yates SC, Zafar A, Rabai EM, Foxall JB, Nagy S, Morrison KE, Clarke C, Esiri MM, Christie S, Smith AD, Nagy Z
The Effects of Two Polymorphisms on p21cip1 Function and Their Association with Alzheimer's Disease in a Population of European Descent.PLoS One. 2015;10(1):e0114050. Epub 2015 Jan 27 PubMed: 25625488
PAPER Serrano-Pozo A, Qian J, Monsell SE, Betensky RA, Hyman BT25623662
PAPER Yang H, Guan H, Yang M, Liu Z, Takeuchi S, Yanagisawa D, Vincent SR, Zhao S, Tooyama I
Upregulation of Mitochondrial Ferritin by Proinflammatory Cytokines: Implications for a Role in Alzheimer's Disease.J Alzheimers Dis. 2015 Jan 26; PubMed: 25624418
PAPER Michele S, Salluzzo MG, Calogero AE, Raffaele F, Bosco P
Association study of COX-2 (PTGS2)-765 G/C promoter polymorphism by pyrosequencing in Sicilian patients with Alzheimer's disease.Arch Med Sci. 2014 Dec 22;10(6):1235-8. PubMed: 25624863
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