PAPER Shin S, Kim JH, Cho JH, Kim GS, Choi SA, Lee JH, For the Alzheimer’s Disease Neuroimaging Initiative
SEARCH RESULTS
329930 RESULTS
PAPER Liu L, Zhang K, Tan L, Chen YH, Cao YP
Alterations in Cholesterol and Ganglioside GM1 Content of Lipid Rafts in Platelets From Patients With Alzheimer Disease.
Alzheimer Dis Assoc Disord. 2014 Apr 22; PubMed: 24759545PAPER Mormont E, Jamart J, Jacques D
Symptoms of Depression and Anxiety After the Disclosure of the Diagnosis of Alzheimer Disease.
J Geriatr Psychiatry Neurol. 2014 Apr 22; PubMed: 24759087PAPER Zhang J, Zhou X, Yu Q, Yang L, Sun D, Zhou Y, Liu J
Epigallocatechin-3-gallate (EGCG)-stabilized selenium nanoparticles coated with Tet-1 peptide to reduce amyloid-β aggregation and cytotoxicity.
ACS Appl Mater Interfaces. 2014 Jun 11;6(11):8475-87. Epub 2014 May 1 PubMed: 24758520PAPER Qu J, Zhou Q, Du Y, Zhang W, Bai M, Zhang Z, Xi Y, Li Z, Miao J
Rutin protects against cognitive deficits and brain damage in rats with chronic cerebral hypoperfusion.
Br J Pharmacol. 2014 Aug;171(15):3702-15. PubMed: 24758388PAPER Liu YJ, Fu Y
[Progress of experimental research on treating Alzheimer's disease by acupuncture].
Zhongguo Zhong Xi Yi Jie He Za Zhi. 2014 Mar;34(3):359-61. PubMed: 24758091PAPER Chung YG, Eum JH, Lee JE, Shim SH, Sepilian V, Hong SW, Lee Y, Treff NR, Choi YH, Kimbrel EA, Dittman RE, Lanza R, Lee DR
Human somatic cell nuclear transfer using adult cells.
Cell Stem Cell. 2014 Jun 5;14(6):777-80. Epub 2014 Apr 17 PubMed: 24746675Roslyn Stanford
Calwell, Australia
Does Dendritic Tau Promote Plasticity?
RESEARCH NEWS 2014-04-25 Research News In Alzheimer’s brains, the axonal protein tau strays into dendritic spines and stirs up trouble at synapses. Researchers have called this a mislocalization, but a paper in the April 23 Journal of Neuroscience challenges this view, suggesting
Hans Zempel on Activity-dependent tau protein translocation to excitatory synapse is disrupted by exposure to amyloid-beta oligomers.
COMMENT This study from the Buisson lab adds more data arguing that tau may contribute to the regulation of synaptic plasticity. It has long been known that tau can bind to f-actin, particularly when phosphorylated at the KXGS-motifs (Mandelkow et al., 2004; Whit
C9ORF72 Repeats Expand into New Disorders—Cause, or Coincidence?
RESEARCH NEWS 2014-04-25 Research News Long repeat sequences in the C9ORF72 gene have cropped up in cases of multiple system atrophy (MSA) and depressive pseudodementia, according to two new case studies. The findings, published in JAMA Neurology on April 14 and 21, respectively,
Barbara Elmer
Germany
PAPER MacArthur DG, Manolio TA, Dimmock DP, Rehm HL, Shendure J, Abecasis GR, Adams DR, Altman RB, Antonarakis SE, Ashley EA, Barrett JC, Biesecker LG, Conrad DF, Cooper GM, Cox NJ, Daly MJ, Gerstein MB, Goldstein DB, Hirschhorn JN, Leal SM, Pennacchio LA, Stamatoyannopoulos JA, Sunyaev SR, Valle D, Voight BF, Winckler W, Gunter C
Guidelines for investigating causality of sequence variants in human disease.
Nature. 2014 Apr 24;508(7497):469-76. PubMed: 24759409Jürgen Götz on Activity-dependent tau protein translocation to excitatory synapse is disrupted by exposure to amyloid-beta oligomers.
COMMENT I enjoyed reading this paper. The study adds to the notion that a prime function of tau is that of a scaffolding protein, not only in the axon but also in the dendrite where tau interacts, as this study shows, also with filamentous actin. Interesting is t
Matthew Wynn
University of California San FranciscoSan Francisco, United States
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