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Tg4-42

RESEARCH MODELS Summary The Tg4-42 model was engineered to produce the peptide Aβ 4-42, one of a variety of N-terminally truncated Aβ species identified in the AD brain. The Aβ 4-42 peptide, which begins with a phenylalanine at position 4, may be a particularly abundant

TBA42

RESEARCH MODELS Summary The TBA42 model was designed to produce and secrete an N-terminally truncated Aβ peptide. TBA42, which stands for truncated beta-amyloid 42, specifically encodes an Aβ 3–42 peptide with a glutamine substituted for the naturally occurring glutamate

Xueyun Zheng


University of California Santa Barbara
Santa Barbara, United States

18 Years After Dolly, First Adult Human Cells Cloned

RESEARCH NEWS 2014-04-28 Research News It appears that scientists have finally succeeded in cloning adult human cells, a goal that has tantalized the field since the first successful cloning of an adult mammal, Dolly the sheep, in 1996. Two independent papers report the generatio

Ryan Mehan


Genentech, Inc.
South San Francisco, United States

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