Neuropharmacology Conference: GABAergic Signaling in Health and Disease, 2014

CONFERENCE 2014-11-13 00:00:00-2014-11-14 00:00:00 Sheraton Pentagon City, Arlington, Virginia 13 November 2014 to 14 November 2014 GABAergic signaling plays a critical role in regulating neuronal development, neuronal plasticity, and dynamic network behavior. GABA receptors are also key clinical targets

PAPER Villeda SA, Plambeck KE, Middeldorp J, Castellano JM, Mosher KI, Luo J, Smith LK, Bieri G, Lin K, Berdnik D, Wabl R, Udeochu J, Wheatley EG, Zou B, Simmons DA, Xie XS, Longo FM, Wyss-Coray T

Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice.

Nat Med. 2014 Jun;20(6):659-63. Epub 2014 May 4 PubMed: 24793238

PAPER Hyun I

Policy: Regulate embryos made for research.

Nature. 2014 May 1;509(7498):27-8. PubMed: 24784200

Glymphatic Flow, Sleep, microRNA Are Frontiers in Alzheimer’s Research

CONFERENCE COVERAGE 2014-05-06 Conference Coverage The neurovascular focus of the first Zilkha Symposium on Alzheimer’s Disease and Related Disorders, held April 4 in Los Angeles, started off with talks on the blood-brain barrier and midlife hypertension (parts one and two of this seri

PAPER Klyubin I, Nicoll AJ, Khalili-Shirazi A, Farmer M, Canning S, Mably A, Linehan J, Brown A, Wakeling M, Brandner S, Walsh DM, Rowan MJ, Collinge J

Peripheral administration of a humanized anti-PrP antibody blocks Alzheimer's disease Aβ synaptotoxicity.

J Neurosci. 2014 Apr 30;34(18):6140-5. PubMed: 24790184

PAPER Ushikubo H, Tanimoto Y, Abe K, Asakawa T, Kan T, Akaishi T

3,3',4',5'-tetrahydroxyflavone induces formation of large aggregates of amyloid β protein.

Biol Pharm Bull. 2014;37(5):748-54. PubMed: 24789998

PAPER Maxfield FR

Role of endosomes and lysosomes in human disease.

Cold Spring Harb Perspect Biol. 2014 May 1;6(5):a016931. PubMed: 24789821

PAPER Saito R, Kaneko M, Kitamura Y, Takata K, Kawada K, Okuma Y, Nomura Y

Effects of oxidative stress on the solubility of HRD1, a ubiquitin ligase implicated in Alzheimer's disease.

PLoS One. 2014;9(5):e94576. Epub 2014 May 1 PubMed: 24788773

PAPER Baglio F, Griffanti L, Saibene FL, Ricci C, Alberoni M, Critelli R, Villanelli F, Fioravanti R, Mantovani F, D'amico A, Cabinio M, Preti MG, Nemni R, Farina E

Multistimulation Group Therapy in Alzheimer's Disease Promotes Changes in Brain Functioning.

Neurorehabil Neural Repair. 2014 Apr 29; PubMed: 24788581

PAPER Hinney A, Albayrak O, Antel J, Volckmar AL, Sims R, Chapman J, Harold D, Gerrish A, Heid IM, Winkler TW, Scherag A, Wiltfang J, Williams J, Hebebrand J, GERAD Consortium, IGAP Consortium, GIANT Consortium

Genetic variation at the CELF1 (CUGBP, elav-like family member 1 gene) locus is genome-wide associated with Alzheimer's disease and obesity.

Am J Med Genet B Neuropsychiatr Genet. 2014 Jun;165B(4):283-93. Epub 2014 May 1 PubMed: 24788522

PAPER Petry FR, Pelletier J, Bretteville A, Morin F, Calon F, Hébert SS, Whittington RA, Planel E

Specificity of anti-tau antibodies when analyzing mice models of Alzheimer's disease: problems and solutions.

PLoS One. 2014;9(5):e94251. Epub 2014 May 2 PubMed: 24788298

PAPER Ikeda K, Yanagihashi M, Sawada M, Hanashiro S, Kawabe K, Iwasaki Y

Donepezil-induced cervical dystonia in Alzheimer's disease: a case report and literature review of dystonia due to cholinesterase inhibitors.

Intern Med. 2014;53(9):1007-10. Epub 2014 May 1 PubMed: 24785894

PAPER Gómez-Gallego M, Gomez-García J, Ato-García M

Confirmatory factor analysis of the quality of life in Alzheimer's disease scale in patients with Alzheimer's disease.

Exp Aging Res. 2014;40(3):266-79. PubMed: 24785591

PAPER Khalid S, Paul S

Identifying a C-terminal ATP binding sites-based novel Hsp90-Inhibitor in silico: a plausible therapeutic approach in Alzheimer's disease.

Med Hypotheses. 2014 Jul;83(1):39-46. Epub 2014 Apr 13 PubMed: 24785461

PAPER O'Malley TT, Oktaviani NA, Zhang D, Lomakin A, O'Nuallain B, Linse S, Benedek GB, Rowan MJ, Mulder FA, Walsh DM

Aβ dimers differ from monomers in structural propensity, aggregation paths and population of synaptotoxic assemblies.

Biochem J. 2014 Aug 1;461(3):413-26. PubMed: 24785004