PAPER Westman E, Simmons A, Muehlboeck JS, Mecocci P, Vellas B, Tsolaki M, Kłoszewska I, Soininen H, Weiner MW, Lovestone S, Spenger C, Wahlund LO,

AddNeuroMed and ADNI: similar patterns of Alzheimer's atrophy and automated MRI classification accuracy in Europe and North America.

Neuroimage. 2011 Oct 1;58(3):818-28. PubMed: 21763442

PAPER Zimprich A, Benet-Pagès A, Struhal W, Graf E, Eck SH, Offman MN, Haubenberger D, Spielberger S, Schulte EC, Lichtner P, Rossle SC, Klopp N, Wolf E, Seppi K, Pirker W, Presslauer S, Mollenhauer B, Katzenschlager R, Foki T, Hotzy C, Reinthaler E, Harutyunyan A, Kralovics R, Peters A, Zimprich F, Brücke T, Poewe W, Auff E, Trenkwalder C, Rost B, Ransmayr G, Winkelmann J, Meitinger T, Strom TM

A mutation in VPS35, encoding a subunit of the retromer complex, causes late-onset Parkinson disease.

Am J Hum Genet. 2011 Jul 15;89(1):168-75. PubMed: 21763483

PAPER Villemagne VL, Ong K, Mulligan RS, Holl G, Pejoska S, Jones G, O'Keefe G, Ackerman U, Tochon-Danguy H, Chan JG, Reininger CB, Fels L, Putz B, Rohde B, Masters CL, Rowe CC

Amyloid imaging with (18)F-florbetaben in Alzheimer disease and other dementias.

J Nucl Med. 2011 Aug;52(8):1210-7. PubMed: 21764791

PAPER Herholz K, Westwood S, Haense C, Dunn G

Evaluation of a calibrated (18)F-FDG PET score as a biomarker for progression in Alzheimer disease and mild cognitive impairment.

J Nucl Med. 2011 Aug;52(8):1218-26. PubMed: 21764801

PAPER Clark TA, Lee HP, Rolston RK, Zhu X, Marlatt MW, Castellani RJ, Nunomura A, Casadesus G, Smith MA, Lee HG, Perry G

Oxidative Stress and its Implications for Future Treatments and Management of Alzheimer Disease.

Int J Biomed Sci. 2010 Sep;6(3):225-227. PubMed: 21765811

Douglas Feinstein on Amyloid beta peptide-(1-42) induces internalization and degradation of beta2 adrenergic receptors in prefrontal cortical neurons.

COMMENT Xiang and colleagues previously showed that Aβ interacts with β2 adrenergic receptors (β2ARs), which could influence synaptic transmission and signaling. Aβ binding activates β2AR signaling as a partial agonist, but does not interfere with catecholamine b

PAPER Trnovec T, Gajdosik A, Bezek S, Sikl D, Koprda V, Zemánek M, Faberová V

The effect of fractions isolated from Candida albicans on phagocytic activity of the reticuloendothelial system in mice.

J Reticuloendothel Soc. 1977 Aug;22(2):111-20. PubMed: 335065

PAPER Tse D, Takeuchi T, Kakeyama M, Kajii Y, Okuno H, Tohyama C, Bito H, Morris RG

Schema-dependent gene activation and memory encoding in neocortex.

Science. 2011 Aug 12;333(6044):891-5. PubMed: 21737703

Terrence Satterfield

United States

Donny Eisenbach

http://www.eldercarechoice.net
Tyler, United States

PAPER Houle JD, Tom VJ, Mayes D, Wagoner G, Phillips N, Silver J

Combining an autologous peripheral nervous system "bridge" and matrix modification by chondroitinase allows robust, functional regeneration beyond a hemisection lesion of the adult rat spinal cord.

J Neurosci. 2006 Jul 12;26(28):7405-15. PubMed: 16837588

PAPER David S, Aguayo AJ

Axonal elongation into peripheral nervous system "bridges" after central nervous system injury in adult rats.

Science. 1981 Nov 20;214(4523):931-3. PubMed: 6171034

PAPER Bradbury EJ, Moon LD, Popat RJ, King VR, Bennett GS, Patel PN, Fawcett JW, McMahon SB

Chondroitinase ABC promotes functional recovery after spinal cord injury.

Nature. 2002 Apr 11;416(6881):636-40. PubMed: 11948352

Elizabeth J. Bradbury on Functional regeneration of respiratory pathways after spinal cord injury.

COMMENT Researchers led by Professor Jerry Silver at Case Western Reserve University in Cleveland, Ohio, have made an important breakthrough in spinal cord injury research. They used two strategies to try to restore function to adult rats with a spinal cord injur

PAPER Viader A, Golden JP, Baloh RH, Schmidt RE, Hunter DA, Milbrandt J

Schwann cell mitochondrial metabolism supports long-term axonal survival and peripheral nerve function.

J Neurosci. 2011 Jul 13;31(28):10128-40. PubMed: 21752989