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Serotonin Neurons—Culprits in Graft-Related Parkinson Dyskinesia

RESEARCH NEWS 2010-07-02 Research News During the late 1980s and the 1990s, tissue grafts, chosen to replace lost dopaminergic neurons, seemed to show great promise for the treatment of Parkinson disease (PD). Yet the results were mixed: Some patients experienced dramatic improve

Mutant SOD1 Inflames If Not Quenched by Autophagy

RESEARCH NEWS 2010-07-02 Research News Misfolded proteins can gum up the cell’s works by glomming together and boosting inflammation. The cell, in turn, fights back by destroying the aggregated proteins. In the case of amyotrophic lateral sclerosis, the malformed miscreant is oft

St. Louis: ApoE—Receptors, Theories and Therapies

CONFERENCE COVERAGE 2010-07-02 Conference Coverage ApoE stands out for a frustrating mark of distinction. Despite its established status as the strongest genetic risk factor for late-onset Alzheimer disease, scientists digging for the why and the how have unearthed a myriad of potentia

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