178007 RESULTS

Crucial Cluster: MicroRNAs Keep Motor Neurons Alive

RESEARCH NEWS 2015-05-22 Research News Motor neurons vary in their sensitivity to neurodegeneration in amyotrophic lateral sclerosis, with the neurons innervating the lateral motor column among the most susceptible. How do they differ from other neurons? Perhaps by highly ...

PAPER Omura T, Omura K, Tedeschi A, Riva P, Painter MW, Rojas L, Martin J, Lisi V, Huebner EA, Latremoliere A, Yin Y, Barrett L, Singh B, Lee S, Crisman T, Gao F, Li S, Kapur K, Geschwind DH, Kosik KS, Coppola G, He Z, Carmichael T, Benowitz LI, Costigan M, Woolf CJ

Robust axonal regeneration occurs in the injured CAST/Ei mouse CNS

Neuron. 2015 Jun 3;86.

What Goes Down Just Went Up: Aβ Climbs in CSF Just Before Dropping

RESEARCH NEWS 2015-05-21 Research News The concentration of Aβ in the cerebrospinal fluid climbs temporarily just as the first plaques appear in the brain. Only after scaling this little peak does it gradually begin its well-known downward slope as plaques hog more Aβ and clog up ...

Protein Screen Links Mitochondrial Regulator to Alzheimer’s Disease

RESEARCH NEWS 2015-05-21 Research News How do proteins linked to neurodegenerative disease heighten risk? One way to answer this question is by looking at the company they keep. In the May 19 Cell Reports, researchers led by Matthias Selbach at the Max Delbrück Center for ...

PAPER Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D

Large-scale mapping of human protein-protein interactions by mass spectrometry.

Mol Syst Biol. 2007;3:89. Epub 2007 Mar 13 PubMed: 17353931

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