DC: Protein Work Expands ALS/FTD Genetics

CONFERENCE COVERAGE 2011-11-25 Conference Coverage At RNA-Binding Proteins in Neurological Disease, a satellite of the annual meeting of the Society for Neuroscience, held 10-11 November 2011 in Arlington, Virginia, researchers reported big new discoveries in ALS genetics. Among the pr

PAPER Jeon SM, Cheon SM, Bae HR, Kim JW, Kim SU

Selective susceptibility of human dopaminergic neural stem cells to dopamine-induced apoptosis.

Exp Neurobiol. 2010 Dec;19(3):155-64. PubMed: 22110355

PAPER Cereda E, Barichella M, Pedrolli C, Klersy C, Cassani E, Caccialanza R, Pezzoli G

Diabetes and risk of Parkinson's disease: a systematic review and meta-analysis.

Diabetes Care. 2011 Dec;34(12):2614-23. PubMed: 22110170

PAPER Xing S, Zhang Y, Li J, Zhang J, Li Y, Dang C, Li C, Fan Y, Yu J, Pei Z, Zeng J

Beclin 1 knockdown inhibits autophagic activation and prevents the secondary neurodegenerative damage in the ipsilateral thalamus following focal cerebral infarction.

Autophagy. 2012 Jan 1;8(1) PubMed: 22108007

PAPER Nagode DA, Tang AH, Karson MA, Klugmann M, Alger BE

Optogenetic release of ACh induces rhythmic bursts of perisomatic IPSCs in hippocampus.

PLoS One. 2011;6(11):e27691. PubMed: 22110723

PAPER Zheng M, Gorelenkova O, Yang J, Feng Z

A liquid phase based C. elegans behavioral analysis system identifies motor activity loss in a nematode Parkinson's disease model.

J Neurosci Methods. 2012 Mar 15;204(2):234-7. PubMed: 22108336

PAPER Little AR, Miller DB, Li S, Kashon ML, O'Callaghan JP

Trimethyltin-induced neurotoxicity: Gene expression pathway analysis, q-RT-PCR and immunoblotting reveal early effects associated with hippocampal damage and gliosis.

Neurotoxicol Teratol. 2012 Jan;34(1):72-82. PubMed: 22108043

PAPER Freeman LR, Granholm AC

Vascular changes in rat hippocampus following a high saturated fat and cholesterol diet.

J Cereb Blood Flow Metab. 2011 Nov 23; PubMed: 22108721

PAPER Byers B, Cord B, Nguyen HN, Schüle B, Fenno L, Lee PC, Deisseroth K, Langston JW, Pera RR, Palmer TD

SNCA triplication Parkinson's patient's iPSC-derived DA neurons accumulate α-synuclein and are susceptible to oxidative stress.

PLoS One. 2011;6(11):e26159. PubMed: 22110584

PAPER Matsumoto Y, Tsunekawa Y, Nomura T, Suto F, Matsumata M, Tsuchiya S, Osumi N

Differential proliferation rhythm of neural progenitor and oligodendrocyte precursor cells in the young adult hippocampus.

PLoS One. 2011;6(11):e27628. PubMed: 22110700

PAPER Viader A, Wright-Jin EC, Vohra BP, Heuckeroth RO, Milbrandt J

Differential regional and subtype-specific vulnerability of enteric neurons to mitochondrial dysfunction.

PLoS One. 2011;6(11):e27727. PubMed: 22110743

PAPER Bové J, Perier C

Neurotoxin-based models of Parkinson's disease.

Neuroscience. 2011 Nov 10; PubMed: 22108613

PAPER Choi HK, Chung KC

Dyrk1A Positively Stimulates ASK1-JNK Signaling Pathway during Apoptotic Cell Death.

Exp Neurobiol. 2011 Mar;20(1):35-44. PubMed: 22110360

PAPER Dubourg O, Wanschitz J, Maisonobe T, Béhin A, Allenbach Y, Herson S, Benveniste O

Diagnostic value of markers of muscle degeneration in sporadic inclusion body myositis.

Acta Myol. 2011 Oct;30(2):103-8. PubMed: 22106712

PAPER Shimada A, Hashimoto H, Kawabe J, Higashiyama S, Kai T, Kataoka K, Tagawa R, Kawarada Y, Nakanishi A, Inoue K, Shiomi S, Kiriike N

Evaluation of therapeutic response to donepezil by positron emission tomography.

Osaka City Med J. 2011 Jun;57(1):11-9. PubMed: 22106763