SEARCH RESULTS

330889 RESULTS

PAPER Alcalay RN, Mirelman A, Saunders-Pullman R, Tang MX, Mejia Santana H, Raymond D, Roos E, Orbe-Reilly M, Gurevich T, Bar Shira A, Gana Weisz M, Yasinovsky K, Zalis M, Thaler A, Deik A, Barrett MJ, Cabassa J, Groves M, Hunt AL, Lubarr N, San Luciano M, Miravite J, Palmese C, Sachdev R, Sarva H, Severt L, Shanker V, Swan MC, Soto-Valencia J, Johannes B, Ortega R, Fahn S, Cote L, Waters C, Mazzoni P, Ford B, Louis E, Levy O, Rosado L, Ruiz D, Dorovski T, Pauciulo M, Nichols W, Orr-Urtreger A, Ozelius L, Clark L, Giladi N, Bressman S, Marder KS

Parkinson disease phenotype in Ashkenazi Jews with and without LRRK2 G2019S mutations.

Mov Disord. 2013 Dec;28(14):1966-71. Epub 2013 Oct 15 PubMed: 24243757

APP(V642I)KI

RESEARCH MODELS Modification Details Targeted knock-in of the V642I mutation into exon 17 of the mouse APP gene using homologous recombination and the Cre-loxP system. Neuropathology Increased Aβ42(43) relative to Aβ40 at 29 months, but without neuritic plaques, neurofib

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