PAPER Knopman DS, Jack CR, Wiste HJ, Weigand SD, Vemuri P, Lowe VJ, Kantarci K, Gunter JL, Senjem ML, Mielke MM, Roberts RO, Boeve BF, Petersen RC

Selective Worsening of Brain Injury Biomarker Abnormalities in Cognitively Normal Elderly Persons With β-Amyloidosis.

JAMA Neurol. 2013 Aug 1;70(8):1030-8. PubMed: 23797806

PAPER Yang W, Wang X, Duan C, Lu L, Yang H

Alpha-synuclein overexpression increases phospho-protein phosphatase 2A levels via formation of calmodulin/Src complex.

Neurochem Int. 2013 Sep;63(3):180-94. PubMed: 23796501

PAPER Hitchler MJ, Domann FE

Regulation of CuZnSOD and Its Redox Signaling Potential: Implications for Amyotrophic Lateral Sclerosis.

Antioxid Redox Signal. 2013 Aug 1; PubMed: 23795822

PAPER Blacker D

Food for Thought.

JAMA Neurol. 2013 Jun 17;:1-3. PubMed: 23779081

lisa oconnor

United States

Etsuro Matsubara on Effect of apolipoprotein e genotype and diet on apolipoprotein e lipidation and amyloid peptides: randomized clinical trial.

COMMENT This is an interesting study showing that both soluble Aβ and apolipoprotein E (ApoE) exist in lipid-depleted cerebrospinal fluid (CSF), and that ApoE4 is linked to cognitive impairment. The results fit well with what we have hypothesized for 20 years: Pa

Etsuro Matsubara

Hirosaki University
Hirosaki, Japan

didin zudiyan

Indonesia

Does a Better Diet Change Aβ in the CSF?

RESEARCH NEWS 2013-06-26 Research News A small pilot study led by Suzanne Craft, Wake Forest University School of Medicine, Winston-Salem, North Carolina, hints that a diet low in simple sugars and saturated fats reduces toxic forms of Aβ in the cerebrospinal fluid (CSF). The fin

Nature Neuroscience Highlights Modern Lab Tools

RESEARCH NEWS 2013-06-26 Research News For the latest neuroscience techniques, their advantages and challenges, check out the June 25 online issue of Nature Neuroscience. In a series of eight reviews, titled "Focus on Neurotechniques," researchers describe how approache

PAPER Buchan JR, Kolaitis RM, Taylor JP, Parker R

Eukaryotic stress granules are cleared by autophagy and Cdc48/VCP function.

Cell. 2013 Jun 20;153(7):1461-74. PubMed: 23791177

PAPER Todd TW, Lim J

Aggregation formation in the polyglutamine diseases: Protection at a cost?

Mol Cells. 2013 Sep;36(3):185-94. PubMed: 23794019

PAPER Park SH, Kukushkin Y, Gupta R, Chen T, Konagai A, Hipp MS, Hayer-Hartl M, Hartl FU

PolyQ proteins interfere with nuclear degradation of cytosolic proteins by sequestering the Sis1p chaperone.

Cell. 2013 Jul 3;154(1):134-45. PubMed: 23791384

PAPER Sharma S, Moon CS, Khogali A, Haidous A, Chabenne A, Ojo C, Jelebinkov M, Kurdi Y, Ebadi M

Biomarkers in Parkinson's disease (recent update).

Neurochem Int. 2013 Sep;63(3):201-29. PubMed: 23791710

PAPER Shi J, Tian J, Zhang X, Zeng C, Wei M, Wang P, Wang Y

A combination extract of Renshen (Panax Ginseng), Yinyanghuo (Herba Epimedii Brevicornus), Yuanzhi (Radix Palygalae) and Jianghuang (Rhizoma Curcumae Longae) decreases glycogen synthase kinase 3beta expression in brain cortex of APPV7171 transgenic mice.

J Tradit Chin Med. 2013 Apr;33(2):211-7. PubMed: 23789219