CONFERENCE 2005-05-17 00:00:00-2005-05-19 00:00:00 Boston, MA, U.S.A. 17 – 19 May 2005 The Bio-IT World Conference program provides a unique educational forum for life science professionals to learn first-hand how the leading pharmaceutical and biotechnology organizations utilize technologies to
CONFERENCE 2005-05-10 00:00:00-2005-05-12 00:00:00 Washington, D.C. Convention Center, Washington, DC, U.S.A 10 – 12 May 2005 PharmaDiscovery will convey the scientific expertise and global reach of Elsevier in a knowledge-based forum, combining pure scientific insight with drug discovery techno
CONFERENCE 2005-05-04 00:00:00-2005-05-05 00:00:00 Genomic and Proteomic Sample Preparation 04 – 05 May 2005 The quality and efficiency of the preparation of genomic and proteomic samples is a key factor for producing high-throughput data of optimal quality. To be successful, it is critical to i
CONFERENCE 2005-05-04 00:00:00-2005-05-05 00:00:00 World Trade Center, Boston, MA, U.S.A 04 – 05 May 2005 The anticipated FDA's Pharmacogenomic Guidance Document holds the promise that 2005 will be an extraordinary year for the advancement of the capabilities of microarrays. Microarrays bui
CONFERENCE 2005-05-03 00:00:00-2005-05-04 00:00:00 World Trade Center, Boston, MA, U.S.A. 03 – 04 May 2005 Technical advances in the ability to extract and analyze molecular material have led to an increased interest in and utilization of tissue. However, tissue samples are a precious commodity.
CONFERENCE 2005-05-02 00:00:00-2005-05-02 00:00:00 New York Academy of Sciences, New York, NY, U.S.A. 02 May 2005 Each day we are exposed to a myriad of events, many of which are routine, and some of which are exceptional. Only a fraction of these events are privileged to become encoded into our long-term
CONFERENCE 2005-05-02 00:00:00-2005-05-03 00:00:00 World Trade Center, Boston, MA, U.S.A. 02 – 03 May 2005 Laser capture microscopy techniques have increased the ease of isolating specific cells or organelles for subsequent molecular analysis. Applications abound from defining new molecular targ
CONFERENCE 2005-05-01 00:00:00-2005-05-04 00:00:00 Melbourne, Australia 01 – 04 May 2005 braininjury@icms.com.au 0
MUTATIONS MAPT 44087767 GRCh37/hg19 G T g.123802G> T g.120981G> T Exon 10 Point, Missense Coding Affects exon 10 splicing, causing an overproduction of 4-repeat (4R) tau isoforms. Extensive neuronal loss in the medial temporal cortex, hippocampus, and amygdal
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MUTATIONS MAPT 44087767 GRCh37/hg19 rs63751165 G A 123802G> A 120981G> A Exon 10 Point, Missense Coding Stem-loop instability leading to alterations in the ratio of 3-repeat (3R) tau to 4-repeat (4R) tau. Reduced lysosomal degradation of tau. Numerous neurofi