SEARCH RESULTS

330988 RESULTS

APP(V642I)KI

RESEARCH MODELS Modification Details Targeted knock-in of the V642I mutation into exon 17 of the mouse APP gene using homologous recombination and the Cre-loxP system. Neuropathology Increased Aβ42(43) relative to Aβ40 at 29 months, but without neuritic plaques, neurofib

Help & FAQs

Other The new Alzforum has launched, and we couldn’t be more excited!  To prepare for this event, we took the time to anticipate a few questions you might have. Do I have to do anything differently to get to the website? No. Alzforum will still be at the same U

About the Team

Other Gabrielle Strobel, Executive Editor Gabrielle Strobel oversees Alzforum's editorial operations, including research and conference reporting, expert commentary, and webinar discussions. She initiated the AlzBiomarkers database and curates the Therapeu

ArcAβ

RESEARCH MODELS Modification Details These mice overexpress human APP695 with the Swedish (K670N/M671L) and Arctic (E693G) mutations. Neuropathology By six months of age, these mice develop amyloid pathology affecting both the brain parenchyma and vasculature. In the par

Current Filters

No filters selected

Filter By

DATE RANGE
  • All
  • Past 7 Days
  • Past 30 Days
  • Past 90 Days
  • Past 12 Months
  • Specific Dates
    1. From
      To

TYPE