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Capillary Clearing—Novel Mechanism a Link to Vascular Dementia?

RESEARCH NEWS 2010-07-09 Research News Emboli can be deadly if they clog up a major artery. Blockages in smaller arterioles and capillaries can have serious consequences, too, especially if enough of them occur among the microvessels that keep voracious neurons in the brain fed w

Mouse Screen Yields Pro-neurogenesis Elixir

RESEARCH NEWS 2010-07-09 Research News Scientists on an optimistic fishing expedition, involving 1,000 small molecules and hundreds of mice, have caught a big one with a chemical that promotes adult neurogenesis. Researchers from the University of Texas Southwestern Medical Cente

Aging Primates—Brain Iron Up, Motor Skills and Plastic Synapses Down

RESEARCH NEWS 2010-07-09 Research News Much of our understanding of Alzheimer disease has come from studies of small, scampering creatures, namely mice, that normally age without racking up plaques or tangles. But in comparison to people, rodents have but a tiny cortex, which is

Research Brief: Clusterin Grabs Spotlight Among Elite Few LOAD Genes

RESEARCH NEWS 2010-07-09 Research News Among the few genes recently linked to late-onset Alzheimer disease (LOAD) in multiple genomewide screens (see Seshadri et al., 2010; Carrasquillo et al., 2010; Corneveaux et al., 2010), clusterin has stolen the show in two new papers. In th

PAPER Schmidt R, Marksteiner M, Dal-Bianco P, Ransmayr G, Bancher C, Benke T, Wancata J, Fischer P, Leblhuber CF, Psota G, Ackerl M, Alf C, Berek K, Croy A, Delazer M, Fasching P, Frühwald T, Fruhwürth G, Fuchs-Nieder B, Gatterer G, Grossmann J, Hinterhuber H, Iglseder B, Imarhiagbe D, Jagsch C, Jellinger K, Kalousek M, Kapeller P, Ladurner G, Lampl C, Lechner A, Lingg A, Nakajima T, Rainer M, Reisecker F, Spatt J, Walch T, Uranüs M, Walter A

[Consensus statement "Dementia 2010" of the Austrian Alzheimer Society].

Neuropsychiatr. 2010;24(2):67-87. PubMed: 20605003

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