Too Many “Burdensome Transitions” for Nursing Home Residents?

RESEARCH NEWS 2011-10-03 Research News Comfort—it’s what family members want most for their bedridden loved ones with advanced dementia. Yet according to a study in the New England Journal of Medicine, the final days for nursing home residents in this situation are often far from

Wake Up and Smell the...Neurodegeneration? AD Model Causes Cell Loss

RESEARCH NEWS 2011-10-03 Research News Though AD pathology is nothing to sniff at, some features, notably neurodegeneration, have been vexingly hard to reproduce in animal models. Researchers at the National Institutes of Health, Bethesda, Maryland, have created a mouse model tha

PAPER Grabowski DC

Medicare and Medicaid: conflicting incentives for long-term care.

Milbank Q. 2007 Dec;85(4):579-610. PubMed: 18070331

PAPER Kane RL, Keckhafer G, Flood S, Bershadsky B, Siadaty MS

The effect of Evercare on hospital use.

J Am Geriatr Soc. 2003 Oct;51(10):1427-34. PubMed: 14511163

PAPER Kane RL, Flood S, Bershadsky B, Keckhafer G

Effect of an innovative medicare managed care program on the quality of care for nursing home residents.

Gerontologist. 2004 Feb;44(1):95-103. PubMed: 14978325

PAPER Ouslander JG, Lamb G, Tappen R, Herndon L, Diaz S, Roos BA, Grabowski DC, Bonner A

Interventions to reduce hospitalizations from nursing homes: evaluation of the INTERACT II collaborative quality improvement project.

J Am Geriatr Soc. 2011 Apr;59(4):745-53. PubMed: 21410447

PAPER Ravits JM, La Spada AR

ALS motor phenotype heterogeneity, focality, and spread: deconstructing motor neuron degeneration.

Neurology. 2009 Sep 8;73(10):805-11. PubMed: 19738176

PAPER Münch C, Bertolotti A

Self-propagation and transmission of misfolded mutant SOD1: prion or prion-like phenomenon?

Cell Cycle. 2011 Jun 1;10(11):1711. PubMed: 21471733

Hilal Lashuel on α-Synuclein occurs physiologically as a helically folded tetramer that resists aggregation.

COMMENT Reply to Selkoe Comment In Dr. Selkoe's comment above, he writes: "First, Dr. Lashuel suggested that one should run the denatured recombinant protein side by side with cell extracts. That is just what we did, and showed in Supp. Fig. S5 A and B.

PAPER Potter VR

Hormonal induction of enzyme functions, cyclic AMP levels and AIB transport in Morris hepatomas and in normal liver systems.

Adv Exp Med Biol. 1977 May 22-24;92:59-87. PubMed: 24990

PAPER Nerup J

HLA studies in diabetes mellitus: a review.

Adv Metab Disord. 1978;9:263-77. PubMed: 347906

PAPER Mosher DF

Action of fibrin-stabilizing factor on cold-insoluble globulin and alpha2-macroglobulin in clotting plasma.

J Biol Chem. 1976 Mar 25;251(6):1639-45. PubMed: 56335

PAPER Kumfor F, Miller L, Lah S, Hsieh S, Savage S, Hodges JR, Piguet O

Are you really angry? The effect of intensity on facial emotion recognition in frontotemporal dementia.

Soc Neurosci. 2011 Oct;6(5-6):502-14. PubMed: 21957889

PAPER Gemma C, Bachstetter AD, Bickford PC

Neuron-Microglia Dialogue and Hippocampal Neurogenesis in the Aged Brain.

Aging Dis. 2010 Dec 1;1(3):232-244. PubMed: 21961084

PAPER Jellinger K

Heterogenous mechanisms of mild cognitive impairment in Parkinson's disease.

J Neural Transm. 2011 Sep 30; PubMed: 21960008