PAPER Koscova S, Zakova Slivarichova D, Tomeckova I, Melicherova K, Stelzer M, Janakova A, Kosorinova D, Belay G, Mitrova E
Cerebrospinal Fluid Biomarkers in the Diagnosis of Creutzfeldt-Jakob Disease in Slovak Patients: over 10-Year Period Review.Mol Neurobiol. 2016 Sep 24; PubMed: 27665282
PAPER Sil S, Ghosh T, Gupta P, Ghosh R, Kabir SN, Roy A
Dual Role of Vitamin C on the Neuroinflammation Mediated Neurodegeneration and Memory Impairments in Colchicine Induced Rat Model of Alzheimer Disease.J Mol Neurosci. 2016 Sep 24; PubMed: 27665568
PAPER Antonsdottir IM, Makino KM, Porsteinsson AP27665036
University of UtahSalt Lake City, United States
Rawan Tarawneh on Diagnostic and Prognostic Utility of the Synaptic Marker Neurogranin in Alzheimer Disease.
COMMENT I'd like to thank Dr. Zetterberg for his comment, and agree with it overall. However, this paper does contain novel information regarding the value of neurogranin as a preclinical biomarker for AD, and its ability to predict future cognitive ...
COMMENT We would like to emphasize that the APP knock-in mice do not display any tau pathology or neurodegeneration. This suggests that Aβ pathology might account, at least in part, for cognitive dysfunction in AD via disturbance of neuronal activities, because ...
COMMENT The research conducted by Dr. Saido and his colleagues is long overdue, relevant, and gets to the heart of the problem of using overexpressing APP models. There is now sufficient data to indicate the neurotropic properties of APP and Aβ and why strategies ...
COMMENT I read with considerable interest the paper of Saido and colleagues describing the lack of calpain activation, p25 accumulation, and tau pathology in their mutant APP knock-in mouse line. Relevant to the discussion surrounding the validity of these ...
COMMENT Excellent story on NIA's Division of Neuroscience and a great profile on Eliezer and his vision for the future of AD research funding. I point out two references, below, regarding the the early history of "program development" on brain ...
PAPER Khachaturian ZS
A chapter in the development of Alzheimer's disease research: a case study of public policies on the development and funding of research programs.Alzheimers Dement. 2007 Jul;3(3):243-58. PubMed: 19595945
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