PAPER Zanto TP, Pa J, Gazzaley A

Reliability measures of functional magnetic resonance imaging in a longitudinal evaluation of mild cognitive impairment.

Neuroimage. 2014 Jan;84:443-52. PubMed: 24018304

PAPER Marszałek M

Diabetes type 2 and Alzheimer disease- one or two diseases? Mechanisms of association.

Postepy Hig Med Dosw (Online). 2013;67:653-71. PubMed: 24018430

PAPER

Alzheimer disease: Targeting protein synthesis to improve memory function in Alzheimer disease.

Biomed Mater Eng. 2013 Jan 1;23:S1419-25. PubMed: 24018474

PAPER Finke K, Myers N, Bublak P, Sorg C

A biased competition account of attention and memory in Alzheimer's disease.

Philos Trans R Soc Lond B Biol Sci. 2013 Oct 19;368(1628):20130062. PubMed: 24018724

PAPER Su J, Gu J, Dong Z, Mei B

Ibuprofen rescues abnormalities in periodontal tissues in conditional presenilin 1 and presenilin 2 double knockout mice.

Int J Mol Sci. 2013;14(9):18457-69. PubMed: 24018889

PAPER Fletcher E, Raman M, Huebner P, Liu A, Mungas D, Carmichael O, Decarli C

Loss of Fornix White Matter Volume as a Predictor of Cognitive Impairment in Cognitively Normal Elderly Individuals.

JAMA Neurol. 2013 Nov 1;70(11):1389-95. PubMed: 24018960

PAPER Li Y, Qin Y, Chen X, Li W

Exploring the functional brain network of Alzheimer's disease: based on the computational experiment.

PLoS One. 2013;8(9):e73186. PubMed: 24019905

PAPER Ma XY, Yu JT, Tan MS, Sun FR, Miao D, Tan L

Missense variants in CR1 are associated with increased risk of Alzheimer' disease in Han Chinese.

Neurobiol Aging. 2014 Feb;35(2):443.e17-21. PubMed: 24018213

Ts65Dn

RESEARCH MODELS Summary This well-characterized model of Down's syndrome develops elevated APP but lacks appreciable β-amyloid pathology. The mice are aneuploid and carry the translocation chromosome, Mmu17 16 (17 16), as a freely segregating, supernumerary chromoso

TetO-APPSweInd (line 102)

RESEARCH MODELS Summary These mice enable regulated expression of mutant APP using a tet-off system. A tetracycline-responsive promoter drives expression of the APP transgene which carries the Swedish and Indiana mutations. When bred to transgenic mice expressing reverse

TetO-APPSweInd (line 107)

RESEARCH MODELS Summary This mouse enables regulated expression of mutant APP using a tet-off system. A tetracycline-responsive promoter drives the expression of an APP transgene bearing both the Swedish and Indiana mutations. When bred to transgenic mice expressing reve

PAPER Heidinger V, Manzerra P, Wang XQ, Strasser U, Yu SP, Choi DW, Behrens MM

Metabotropic glutamate receptor 1-induced upregulation of NMDA receptor current: mediation through the Pyk2/Src-family kinase pathway in cortical neurons.

J Neurosci. 2002 Jul 1;22(13):5452-61. PubMed: 12097497

PAPER Beraldo FH, Arantes CP, Santos TG, Machado CF, Roffe M, Hajj GN, Lee KS, Magalhães AC, Caetano FA, Mancini GL, Lopes MH, Américo TA, Magdesian MH, Ferguson SS, Linden R, Prado MA, Martins VR

Metabotropic glutamate receptors transduce signals for neurite outgrowth after binding of the prion protein to laminin γ1 chain.

FASEB J. 2011 Jan;25(1):265-79. PubMed: 20876210

Brian Kennedy on Sirt1 Extends Life Span and Delays Aging in Mice through the Regulation of Nk2 Homeobox 1 in the DMH and LH.

COMMENT The role of SIR2 orthologs in modulating longevity is currently a subject of major debate. While overexpression ofSIR2 extends lifespan in yeast, studies in worms and flies remain inconsistent and whole body over expression of the mouse ortholog, SIRT1, f

Brian Kennedy

Buck Institute
United States