PAPER Filali M, Lalonde R, Rivest S

Subchronic memantine administration on spatial learning, exploratory activity, and nest-building in an APP/PS1 mouse model of Alzheimer's disease.

Neuropharmacology. 2011 May;60(6):930-6. PubMed: 21281652

PAPER Naftolin F, Harman SM

Preventing Alzheimer disease and cognitive decline.

Ann Intern Med. 2011 Feb 1;154(3):211-2; author reply 212-3. PubMed: 21282704

PAPER Qiu C, Kivipelto M, Fratiglioni L

Preventing Alzheimer disease and cognitive decline.

Ann Intern Med. 2011 Feb 1;154(3):211; author reply 212-3. PubMed: 21282705

PAPER Tsopelas C, Stewart R, Savva GM, Brayne C, Ince P, Thomas A, Matthews FE,

Neuropathological correlates of late-life depression in older people.

Br J Psychiatry. 2011 Feb;198(2):109-14. PubMed: 21282780

Mariana Vargas-Caballero

University of Southampton
Southampton

Tom Williams

Philadelphia, United States

Daryl Bosco on Decreased stability and increased formation of soluble aggregates by immature superoxide dismutase do not account for disease severity in ALS.

COMMENT The paper by Vassall et al. reminds us that finding a common, toxic characteristic (e.g., aggregation propensity) amongst ALS-linked SOD1 mutants is not straightforward. Moreover, the extrapolation of in vitro aggregation kinetics to human disease pathoge

PAPER Vernooij MW, van der Lugt A, Ikram MA, Wielopolski PA, Niessen WJ, Hofman A, Krestin GP, Breteler MM

Prevalence and risk factors of cerebral microbleeds: the Rotterdam Scan Study.

Neurology. 2008 Apr 1;70(14):1208-14. PubMed: 18378884

PAPER Danfors T, Bergström M, Feltelius N, Ahlström H, Westerberg G, Långström B

Positron emission tomography with 11C-D-deprenyl in patients with rheumatoid arthritis. Evaluation of knee joint inflammation before and after intra-articular glucocorticoid treatment.

Scand J Rheumatol. 1997;26(1):43-8. PubMed: 9057801

CD11b αM Integrin (M1/170.15.1)

ANTIBODY monoclonal M1/170.15.1 manufacturer Cat# MAB1387Z immunogn = T cell enriched splenocytes from B10 mice liquid, protein-G purified, PBS, no preservatives recognizes the murine alphaM integrin chain; stains polymorphonuclear cells, monocytes and NK cells no

CD11b αM Integrin (M1/170.15.1)

ANTIBODY monoclonal M1/170.15.1 manufacturer Cat# CBL1313 immunogn = B10 mouse spleen cells enriched with T cells liquid, purified, PBS, azide<br />Also available Phycoerythrin conjugated, CBL1313P specific to CD11b; recognizes a differentiation antigen situ

CD11b αM Integrin (ICO-GM1)

ANTIBODY monoclonal ICO-GM1 manufacturer Cat# MAB2117<br />Reference: <br />(<a href="/papers/regulation-tau-pathology-microglial-fractalkine-receptor" target="_new">Bhaskar K, 2010</a>, mouse anti-CD11b, but see also CB

Terrence Town on CD45 deficiency drives amyloid-β peptide oligomers and neuronal loss in Alzheimer's disease mice.

COMMENT Reply to comment by Donna Wilcock I wanted to respond briefly to the thought-provoking comments by Donna Wilcock. We, too, were struck by the parallels between our study and her and Carol Colton’s work on NOS2 deletion in APP transgenic mice. It is striki

Mind the IGAP—Transatlantic Consortium to Map AD Genes

RESEARCH NEWS 2011-02-02 Research News The first human genome sequence came out—to much fanfare—10 years ago this month. Fitting that anniversary mode, then, is the launch yesterday of the International Genomics of Alzheimer’s Project (IGAP), an international collaboration that a

X-raying Aβ Oligomers, Unraveling Mysteries of Amyloid Aggregation

RESEARCH NEWS 2011-02-02 Research News Amyloid sure likes to keep its secrets. Despite decades of research, scientists still do not know precisely what makes amyloidogenic molecules such as Aβ gang up and go bad. Two new papers yield some clues to the puzzle. In the January 26 Jo