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APP V562I

MUTATIONS APP 27326907 GRCh37/hg19 rs199586073 G A Exon 13 Point, Missense Coding In cells, Aβ40 secretion was slightly decreased with no change in Aβ42 secretion. Aβ42/Aβ40 was not significantly different from controls. Not applicable. V562I Alzheimer's Disea

Averting a Late-life Crisis: Midlife ApoE2 Clears Plaques in Mice

RESEARCH NEWS 2013-11-23 Research News ApoE’s complex links to Aβ pathology have engendered debate about whether modulating this lipoprotein makes for a rational treatment strategy in Alzheimer’s disease. Animal studies show that ApoE, depending on the isoform, either heightens o

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