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Brian Popko on Oligodendrocyte Support System Fails Early in ALS

COMMENT This is a very well-done study that provides strong evidence that oligodendrocytes, the cells responsible for myelinating the central nervous system, contribute to disease pathogenesis in ALS. This is particularly exciting because it demonstrates a critic

Cholinergic Neurons From Stem Cells Rescue Mouse Memories

RESEARCH NEWS 2013-04-26 Research News A new recipe for cooking up cholinergic neurons from stem cells may help researchers study what goes wrong with these cells in Alzheimer’s disease. In the April 21 Nature Biotechnology online, researchers led by Su-Chun Zhang at the Universi

Newborn Healers—Novel Astrocytes Repair Brain Injury

RESEARCH NEWS 2013-04-26 Research News When leaky blood vessels damage the brain, the organ’s stem cell niche dispatches a specialist crew of astrocytes to stop the bleeding, reports a paper in the April 24 Nature online. These novel glia appear essential for proper recovery. The

Does Progranulin Play Both Sides in AD and FTD?

RESEARCH NEWS 2013-04-26 Research News Mutations that cause frontotemporal dementia may also predispose carriers to Alzheimer’s dementia, according to a paper in the April 22 JAMA Neurology online. Previous genetic studies have suggested that progranulin mutations increase risk f

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