PAPER Cassel JC, Gaurivaud M, Lazarus C, Bertrand F, Galani R, Jeltsch H
SEARCH RESULTS
330059 RESULTS
PAPER Leanza G, Martìnez-Serrano A, Björklund A
Amelioration of spatial navigation and short-term memory deficits by grafts of foetal basal forebrain tissue placed into the hippocampus and cortex of rats with selective cholinergic lesions.
Eur J Neurosci. 1998 Jul;10(7):2353-70. PubMed: 9749764PAPER Gage FH, Björklund A, Stenevi U, Dunnett SB, Kelly PA
Intrahippocampal septal grafts ameliorate learning impairments in aged rats.
Science. 1984 Aug 3;225(4661):533-6. PubMed: 6539949Brian Popko on Oligodendrocyte Support System Fails Early in ALS
COMMENT This is a very well-done study that provides strong evidence that oligodendrocytes, the cells responsible for myelinating the central nervous system, contribute to disease pathogenesis in ALS. This is particularly exciting because it demonstrates a critic
Brian Popko
University of ChicagoUnited States
Cynthia Lemere on Aβ Vaccine Leads to Safer Immune Response in Mice
COMMENT The article by Browne et al. under "Related Papers" (Browne et al., 2013) directly addresses why it may be beneficial not only reduce to amyloid-β with targeted antibodies, but also to promote an anti-inflammatory Th2 and T regulatory response t
Takaomi Saido on Brain amyloid-β oligomers in ageing and Alzheimer's disease.
COMMENT The group led by Karen Ashe presents an important finding that Aβ*56, not dimers or trimers, correlate with "pathological tau" proteins and postsynaptic proteins in human brains. Everyone in the AD research field should read this paper carefully
Takaomi Saido on Fluorine-18 radiolabeled heterocycles as PET tracers for imaging β-amyloid plaques in Alzheimer's disease.
COMMENT This is a nice update of [18F]-labeled PET ligands for amyloid imaging. 0 saido
Takaomi Saido on A transgenic Alzheimer rat with plaques, tau pathology, behavioral impairment, oligomeric aβ, and frank neuronal loss.
COMMENT This work deserves a lot of attention. One thing that is unclear is the definition of tauopathy. 0 saido
Peter Blackburn
Mercia Pharma, Inc.New York, United States
Saak V. Ovsepian
NIMHPrague , Czech Republic
Cholinergic Neurons From Stem Cells Rescue Mouse Memories
RESEARCH NEWS 2013-04-26 Research News A new recipe for cooking up cholinergic neurons from stem cells may help researchers study what goes wrong with these cells in Alzheimer’s disease. In the April 21 Nature Biotechnology online, researchers led by Su-Chun Zhang at the Universi
Newborn Healers—Novel Astrocytes Repair Brain Injury
RESEARCH NEWS 2013-04-26 Research News When leaky blood vessels damage the brain, the organ’s stem cell niche dispatches a specialist crew of astrocytes to stop the bleeding, reports a paper in the April 24 Nature online. These novel glia appear essential for proper recovery. The
Does Progranulin Play Both Sides in AD and FTD?
RESEARCH NEWS 2013-04-26 Research News Mutations that cause frontotemporal dementia may also predispose carriers to Alzheimer’s dementia, according to a paper in the April 22 JAMA Neurology online. Previous genetic studies have suggested that progranulin mutations increase risk f
PAPER Onyike CU, Huey ED
Frontotemporal dementia and psychiatry.
Int Rev Psychiatry. 2013 Apr;25(2):127-9. PubMed: 23611342Current Filters
No filters selected