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203271 RESULTS

NSE-APP751

RESEARCH MODELS This model was the first reported APP transgenic mouse. It overexpressed the human APP 751 isoform which includes the Kunitz serine protease inhibitor domain. The transgene was expressed throughout the brain from a rat neural-specific enolase (NSE) ...

ITI-007

THERAPEUTICS Add Private note Add An editorial note Bristol-Myers Squibb Intra-Cellular Therapies, Inc. Small Molecule Other Neurotransmitters In 2014, Intra-Cellular Therapies ran a Phase 1/2 dose-escalation study of up to 30 mg/d in 30 old healthy volunteers and ...

In NFL Players, Brain Inflammation May Persist Years After Head Trauma

RESEARCH NEWS 2016-12-02 Add Private note Add An editorial note Research News Research has shown that sports-related head injuries lead to future amyloid and tau pathology, as well as a higher risk of dementia and neuropsychiatric symptoms. However, the link between traumatic ...

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