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Terrence Town on Hot DAM: Specific Microglia Engulf Plaques

COMMENT In addition to the certainty in life of death and taxes, we also have the guarantee of scientific advancements—although sometimes met with intermittent setbacks. This rings true when considering the back-and-forth play with respect to the role of TREM2 in ...

New Alzheimer’s Drug Shows Safety, Hints of Efficacy in Phase 2

RESEARCH NEWS 2017-06-22 Research News A first-in-class Alzheimer’s therapeutic met its primary endpoint in a Phase 2a trial, according to topline results released by the drug’s sponsor, Probiodrug in Halle, Germany. The compound, PQ912, inhibits an enzyme that produces ...

Cristina Muscio on DLB Guidelines Get a Makeover

COMMENT The new guidelines have rightly put greater emphasis on the diagnostic role of REM behavior disorder, which is likely to be the most specific among the “core features.” In addition, a greater diagnostic weight has been given to MIBG myocardial ...

Trigger Warning: α-Synuclein Sets Off T Cells in Parkinson’s

RESEARCH NEWS 2017-06-21 Research News The innate immune system factors heavily in Parkinson’s disease, but evidence has been thinner for its pickier twin, the adaptive immune system. The latter draws renewed suspicion from a paper in the June 21 Nature. In it, scientists led by ...

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