Ethan Craig

Georgia Institute of Technology and Emory University
Atlanta, United States

Vahram (Harry) Haroutunian on Serum ceramides increase the risk of Alzheimer disease: the Women's Health and Aging Study II.

COMMENT A recent longitudinal population-based study of older women by Mielke et al. showed that high serum ceramide levels were associated with an increased risk of all-cause dementia independent of age, blood glucose, and BMI. These findings are consistent with

No Pony in There: Bapi Fails Mild to Moderate ApoE4 Carriers

RESEARCH NEWS 2012-07-23 Research News Today, Pfizer conceded that results of the first of four Phase 3 trials of intravenous bapineuzumab, a monoclonal antibody against Aβ, failed to meet its co-primary endpoints in some 1,100 patients with mild to moderate Alzheimer’s disease w

Research Brief: Certain Serum Ceramides Increase Risk for AD

RESEARCH NEWS 2012-07-23 Research News Results of a nine-year longitudinal study indicate that women with the highest amounts of certain types of ceramide in their blood are more likely to develop Alzheimer’s disease. Researchers led by Michelle Mielke from the Mayo Clinic, Roche

Michael Ewers

Ludwig Maximilian University
Munich, Germany

PAPER Rutherford NJ, Dejesus-Hernandez M, Baker MC, Kryston TB, Brown PE, Lomen-Hoerth C, Boylan K, Wszolek ZK, Rademakers R

C9ORF72 hexanucleotide repeat expansions in patients with ALS from the Coriell Cell Repository.

Neurology. 2012 Jul 31;79(5):482-3. PubMed: 22815561

PAPER Svenningsson P, Westman E, Ballard C, Aarsland D

Cognitive impairment in patients with Parkinson's disease: diagnosis, biomarkers, and treatment.

Lancet Neurol. 2012 Aug;11(8):697-707. PubMed: 22814541

PAPER May VE, Nuber S, Marxreiter F, Riess O, Winner B, Winkler J

Impaired olfactory bulb neurogenesis depends on the presence of human wild-type alpha-synuclein.

Neuroscience. 2012 Oct 11;222:343-55. PubMed: 22814000

PAPER Giorgetti A, Marchetto MC, Li M, Yu D, Fazzina R, Mu Y, Adamo A, Paramonov I, Cardoso JC, Monasterio MB, Bardy C, Cassiani-Ingoni R, Liu GH, Gage FH, Izpisua Belmonte JC

Cord blood-derived neuronal cells by ectopic expression of Sox2 and c-Myc.

Proc Natl Acad Sci U S A. 2012 Jul 31;109(31):12556-61. PubMed: 22814375

PAPER Hogel M, Laprairie RB, Denovan-Wright EM

Promoters are differentially sensitive to N-terminal mutant huntingtin-mediated transcriptional repression.

PLoS One. 2012;7(7):e41152. PubMed: 22815947

PAPER Vlamings R, Benazzouz A, Chetrit J, Janssen ML, Kozan R, Visser-Vandewalle V, Steinbusch HW, von Hörsten S, Temel Y

Metabolic and electrophysiological changes in the basal ganglia of transgenic Huntington's disease rats.

Neurobiol Dis. 2012 Dec;48(3):488-94. PubMed: 22813864

PAPER Reznichenko L, Cheng Q, Nizar K, Gratiy SL, Saisan PA, Rockenstein EM, González T, Patrick C, Spencer B, Desplats P, Dale AM, Devor A, Masliah E

In vivo alterations in calcium buffering capacity in transgenic mouse model of synucleinopathy.

J Neurosci. 2012 Jul 18;32(29):9992-8. PubMed: 22815513

PAPER Kambeitz JP, Bhattacharyya S, Kambeitz-Ilankovic LM, Valli I, Collier DA, McGuire P

Effect of BDNF val(66)met polymorphism on declarative memory and its neural substrate: A meta-analysis.

Neurosci Biobehav Rev. 2012 Oct;36(9):2165-77. PubMed: 22813992

PAPER Oremus M, Tarride JE

Modeling cost-effectiveness of pharmaceuticals in Alzheimer's disease.

Expert Rev Pharmacoecon Outcomes Res. 2012 Jun;12(3):275-7. PubMed: 22812550

PAPER Armstrong RA

Visual signs and symptoms of dementia with Lewy bodies.

Clin Exp Optom. 2012 Jul 19; PubMed: 22812926