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331007 RESULTS

PSEN1 Y154C

MUTATIONS PSEN1 73640396 GRCh37/hg19 rs63751292 A G g.25664A> G g.42218A> G Exon 5 Point, Missense Coding Unknown, but multiple in silico algorithms predicted a damaging effect. Unknown Y154C Alzheimer's Disease: Not ClassifiedAlzheimer's Disease Th

The Blood-Brain Barrier: Getting Drugs into the Brain

CONFERENCE 2005-04-26 00:00:00-2005-04-26 00:00:00 New York Academy of Sciences, New York, NY, U.S.A. 26 April 2005 The blood–brain barrier (BBB) separates the mammalian brain from the systemic circulation and plays a vital role in the homeostasis of the central nervous system (CNS). While disturbances of

MAPT R5H

MUTATIONS MAPT 44039717 GRCh37/hg19 rs63750959 G A g.75756G> A g.72930G> A Exon 1 Point, Missense Coding Reduces tau's ability to promote microtubule assembly; Increases fibril formation in vitro. Neuronal loss in the frontal and temporal lobes; Tau depo

Bioactive Lipids, Lipidomics and their Targets (Z1)

CONFERENCE 2005-04-12 00:00:00-2005-04-17 00:00:00 Fairmont Chateau Whistler, Whistler, British Columbia, Canada 12 &#x2013 17 April 2005 There is an increasing appreciation of the role of lipids as ligands for membrane and nuclear receptors, as intracellular signals and as direct modulators of protei

Keystone Symposium: Systems and Biology (X4)

CONFERENCE 2005-04-08 00:00:00-2005-04-13 00:00:00 Keystone Resort, Keystone, CO, U.S.A. 08 &#x2013 13 April 2005 Biological processes can be considered as complex networks of interconnected components. Thus, to understand network properties involved in development and diseases, one should consider a

Proteomics and Bioinformatics (X3)

CONFERENCE 2005-04-08 00:00:00-2005-04-13 00:00:00 Keystone Resort, Keystone, CO, U.S.A. 08 &#x2013 13 April 2005 Proteomics has emerged as a key discipline in the post-genomic 'tool chest' and over the last few years, proteomics technology has become extraordinarily powerful. Mass spectrome

The New Prion Biology: Basic Science, Diagnosis and Therapy

CONFERENCE 2005-04-07 00:00:00-2005-04-09 00:00:00 IstitutoVeneto di ScienzeLettere e dArti, Venice, Italy 07 &#x2013 09 April 2005 The programme foresees lectures by leading scientists in different aspects of prion diseases, and at least three plenary lectures on topics of protein aggregation/misfold

Axonal Connections: Molecular Cues for Development and Regeneration (C6)

CONFERENCE 2005-03-31 00:00:00-2005-04-04 00:00:00 Beaver Run Resort, Breckenridge, CO, U.S.A. 31 March &#x2013 04 April 2005 The functioning of the nervous system depends on its complex pattern of connections. Axonal connections are initially set up during development by cues, which guide axons along

Roles of TGF-beta in Disease Pathogenesis: Novel Therapeutic Strategies (C4)

CONFERENCE 2005-03-28 00:00:00-2005-04-02 00:00:00 Keystone Resort, Keystone, CO, U.S.A. 28 March &#x2013 02 April 2005 Elucidation of the signal transduction pathways of TGF-b has heralded an exciting new era enabling insights into molecular mechanisms of this multifunctional molecule in both normal

Advances in Mitochondrial and Oxidative Damage in the Pathogenesis of Aging

CONFERENCE 2005-03-21 00:00:00-2005-03-21 00:00:00 New York Academy of Sciences, New York, NY, U.S.A. 21 March 2005 Speakers: Bruce A. Yankner, Childrenís Hospital Boston; and Douglas C. Wallace, University of California, Irvine Organizer: M. Flint Beal, Weill Medical College of Cornell University The Neu

Symposium on New Treatments for Dementia

CONFERENCE 2005-03-10 00:00:00-2005-03-10 00:00:00 New York Academy of Medicine, New York, NY, U.S.A. 10 March 2005 Journalists are welcome to attend a symposium with a comprehensive approach to the latest treatments for dementia. It will focus on the best medicines, new ways to collaborate with family me

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