PAPER Salek RM, Xia J, Innes A, Sweatman BC, Adalbert R, Randle S, McGowan E, Emson PC, Griffin JL
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PAPER Gong QH, Wang Q, Pan LL, Liu XH, Huang H, Zhu YZ
Hydrogen sulfide attenuates lipopolysaccharide-induced cognitive impairment: a pro-inflammatory pathway in rats.
Pharmacol Biochem Behav. 2010 Jul;96(1):52-8. PubMed: 20399805PAPER Egea J, García AG, Verges J, Montell E, López MG
Antioxidant, antiinflammatory and neuroprotective actions of chondroitin sulfate and proteoglycans.
Osteoarthritis Cartilage. 2010 Jun;18 Suppl 1:S24-7. PubMed: 20399898PAPER Despotović N, Erceg P, Potić B, Stojanovic J, Milosević DP, Davidović M
Biogerontology in Serbia.
Biogerontology. 2011 Feb;12(1):11-5. PubMed: 20401693george lundberg
StanfordLos gatos, United States
Craig Atwood on Geneva: At Springfield Meeting, Soul-Searching About Dearth of Drugs
COMMENT Is a Therapeutic Answer to Alzheimer’s Disease Already at Hand? There is one drug that has been shown to consistently improve cognition, both as a prophylactic and as a treatment—that “drug” is 17β-estradiol (see Gleason et al., 2005 for a summary of thes
PAPER Wright DW, Hoffman SW, Virmani S, Stein DG
Effects of medroxyprogesterone acetate on cerebral oedema and spatial learning performance after traumatic brain injury in rats.
Brain Inj. 2008 Feb;22(2):107-13. PubMed: 18240039PAPER Turgeon JL, McDonnell DP, Martin KA, Wise PM
Hormone therapy: physiological complexity belies therapeutic simplicity.
Science. 2004 May 28;304(5675):1269-73. PubMed: 15166356PAPER Paganini-Hill A, Corrada MM, Kawas CH
Increased longevity in older users of postmenopausal estrogen therapy: the Leisure World Cohort Study.
Menopause. 2006 Jan-Feb;13(1):12-8. PubMed: 16607094PAPER Nilsen J, Morales A, Brinton RD
Medroxyprogesterone acetate exacerbates glutamate excitotoxicity.
Gynecol Endocrinol. 2006 Jul;22(7):355-61. PubMed: 16864144PAPER Nilsen J, Brinton RD
Divergent impact of progesterone and medroxyprogesterone acetate (Provera) on nuclear mitogen-activated protein kinase signaling.
Proc Natl Acad Sci U S A. 2003 Sep 2;100(18):10506-11. PubMed: 12925744PAPER Gallego MJ, Porayette P, Kaltcheva MM, Meethal SV, Atwood CS
Opioid and progesterone signaling is obligatory for early human embryogenesis.
Stem Cells Dev. 2009 Jun;18(5):737-40. PubMed: 18803462PAPER Frye CA, Walf AA
Progesterone to ovariectomized mice enhances cognitive performance in the spontaneous alternation, object recognition, but not placement, water maze, and contextual and cued conditioned fear tasks.
Neurobiol Learn Mem. 2008 Jul;90(1):171-7. PubMed: 18455450Kentaro Hayashi
University of Wisconsin-MadisonMadison, United States
A. David Smith on Toronto: 6th Sense—GWAS Picks Up New AD Risk Variant
COMMENT The enzyme MTHFD1L does not directly catalyze the conversion of homocysteine to methionine. Also, there is no current evidence that mutations in the gene for MTHFD1L cause elevated homocysteine levels. The finding that a variant of MTHFD1L is linked to th
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