PAPER Mormont E, Jamart J, Robaye L
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PAPER Takeo K, Watanabe N, Tomita T, Iwatsubo T
Contribution of the γ-secretase subunits to the formation of catalytic pore of presenilin 1 protein.
J Biol Chem. 2012 Jul 27;287(31):25834-43. Epub 2012 Jun 11 PubMed: 22689582PAPER Hammers D, Spurgeon E, Ryan K, Persad C, Barbas N, Heidebrink J, Darby D, Giordani B
Validity of a brief computerized cognitive screening test in dementia.
J Geriatr Psychiatry Neurol. 2012 Jun;25(2):89-99. PubMed: 22689701PAPER Kolarova M, García-Sierra F, Bartos A, Ricny J, Ripova D
Structure and pathology of tau protein in Alzheimer disease.
Int J Alzheimers Dis. 2012;2012:731526. PubMed: 22690349Aaron Gitler on Paper Alert: Stress Granules Get Tangled Up in Tau
COMMENT This manuscript presents a comprehensive analysis of stress granule pathology in mouse models of tauopathies and in postmortem tissue from Alzheimer's disease patients. An important role for defects in RNA metabolism in general, and stress granule pa
John Trojanowski on Paper Alert: Stress Granules Get Tangled Up in Tau
COMMENT The Wolozin group investigates stress granules (SGs) because stress has been shown to induce aggregation of RNA-binding proteins to form SGs. Hence, the researchers asked if SG proteins colocalize with Alzheimer's disease signature lesions, i.e., neu