SEARCH RESULTS

329930 RESULTS

PAPER Janssen HL, Reesink HW, Lawitz EJ, Zeuzem S, Rodriguez-Torres M, Patel K, van der Meer AJ, Patick AK, Chen A, Zhou Y, Persson R, King BD, Kauppinen S, Levin AA, Hodges MR

Treatment of HCV infection by targeting microRNA.

N Engl J Med. 2013 May 2;368(18):1685-94. PubMed: 23534542

APP751SL/PS1 KI

RESEARCH MODELS Modification Details This animal is a cross between a PSEN1 knock-in line and an APP over-expressing line. The PS1 knock-in line was generated by introducing two point mutations in the wild-type mouse PSEN1, corresponding to the mutations M233T and L235P.

A Conference Devoted to Better Engaging Clinical Trial Volunteers

CONFERENCE COVERAGE 2013-11-26 Conference Coverage Clinical trials, particularly for Alzheimer’s disease, often struggle to find participants fast enough and retain them until the trial is over. As more drugs move into Phase 3, this is increasingly seen as a major bottleneck in the mov

Blocking a MicroRNA Slows Motor Neuron Disease in Mice

CONFERENCE COVERAGE 2013-11-26 Conference Coverage Researchers are taking aim at amyotrophic lateral sclerosis with an antisense oligonucleotide targeted toward microRNA (miRNA), those nucleic acid snippets that each regulate hundreds of mRNAs. A single anti-miRNA therapeutic could tun

Current Filters

No filters selected

Filter By

DATE RANGE
  • All
  • Past 7 Days
  • Past 30 Days
  • Past 90 Days
  • Past 12 Months
  • Specific Dates
    1. From
      To

TYPE