330988 RESULTS
ANTIBODY polyclonal manufacturer Cat# LS-C3656<br /> manufacturer: LifeSpan Biosciences immunogen = synthetic peptide corresp. to aa339-348 of the C-terminal region of the human Alzheimer's amyloid precursor protein frameshift mutant liquid, unpurified
ANTIBODY polyclonal manufacturer Cat# LS-C68965<br />manufacturer: LifeSpan Biosciences immunogen = synthetic peptide corresp. to a protein sequence derived from N-terminus of human Amyloid Beta liquid, PBS, BSA, azide, affinity purified recognizes human Amy
ANTIBODY polyclonal manufacturer Cat# LS-C88784<br />manufacturer: LifeSpan Biosciences immunogen = synthetic peptide from aa 8-17 of human amyloid beta-protein liquid, PBS, BSA, azide, affinity purified APP IgG APP, APLP, AICD Autogen Bioclear Rabbit Human
South Natick, United States
McGill UniversityMontreal, Canada
COMMENT The very interesting report by Renner et al. demonstrates Aβ-induced clustering of mGluR5 receptors and suggests that membrane-bound Aβ oligomers interact with mGluR5. Since chemical crosslinking of the receptor and application of Aβ oligomers produce sim
PAPER Popkirov SG, Manahan-Vaughan D
PAPER Traynor BJ, Nalls M, Lai SL, Gibbs RJ, Schymick JC, Arepalli S, Hernandez D, van der Brug MP, Johnson JO, Dillman A, Cookson M, Moglia C, Calvo A, Restagno G, Mora G, Chiò A
PAPER Fukuda T, Yamagata K, Fujiyama S, Matsumoto T, Koshida I, Yoshimura K, Mihara M, Naitou M, Endoh H, Nakamura T, Akimoto C, Yamamoto Y, Katagiri T, Foulds C, Takezawa S, Kitagawa H, Takeyama K, O'Malley BW, Kato S
PAPER Gregory RI, Yan KP, Amuthan G, Chendrimada T, Doratotaj B, Cooch N, Shiekhattar R
PAPER Dostie J, Mourelatos Z, Yang M, Sharma A, Dreyfuss G
COMMENT This is a solid study that provides important confirmation that presenilin is a zymogen that cuts itself (i.e., it is its own “presenilinase”) and that autoproteolysis occurs stepwise, every ~3 amino acids, similar to what is seen with γ-secretase substra
COMMENT I read this news story with sadness. I regret the lack of investigators cooperating on the basis of mutual trust and a handshake. Of course, that is still possible among some, but these days commercial/monetary/legal issues are too often inserted to the d
RESEARCH NEWS 2010-06-29 Research News Sifting through the genome has netted several mutations responsible for motor neuron diseases, but scientists still cannot explain the cause for most incidences. For amyotrophic lateral sclerosis (ALS), an adult-onset condition, genetics exp
ANTIBODY polyclonal manufacturer Cat# LS-B3672<br /> manufacturer: LifeSpan Biosciences immunogen = peptide corresp. to aa737-751 of human amyloid A4 protein precursor (APP) or residues 85-99 of the C99 fragment generated by β- and γ-secretases. liquid, PBS,
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