PAPER Daley GQ, Scadden DT
SEARCH RESULTS
330986 RESULTS
PAPER Hockemeyer D, Wang H, Kiani S, Lai CS, Gao Q, Cassady JP, Cost GJ, Zhang L, Santiago Y, Miller JC, Zeitler B, Cherone JM, Meng X, Hinkley SJ, Rebar EJ, Gregory PD, Urnov FD, Jaenisch R
Genetic engineering of human pluripotent cells using TALE nucleases.
Nat Biotechnol. 2011 Aug;29(8):731-4. PubMed: 21738127PAPER Summers KM
Relationship between genotype and phenotype in monogenic diseases: relevance to polygenic diseases.
Hum Mutat. 1996;7(4):283-93. PubMed: 8723677PAPER Bock C, Kiskinis E, Verstappen G, Gu H, Boulting G, Smith ZD, Ziller M, Croft GF, Amoroso MW, Oakley DH, Gnirke A, Eggan K, Meissner A
Reference Maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines.
Cell. 2011 Feb 4;144(3):439-52. PubMed: 21295703Chicago: 2nd Annual Symposium Explores ApoE
CONFERENCE COVERAGE 2011-07-26 Conference Coverage Download a PDF of this report. Apolipoprotein E (ApoE) gene alleles are the strongest genetic modulators of late-onset Alzheimer's disease (AD) risk. Some 60 percent of AD individuals carry at least one copy of the ApoE4 variant.
Editing Stem Cell DNA to Make the Perfect Cells for Study, Therapy
RESEARCH NEWS 2011-07-26 Research News Now that they can make induced pluripotent stem cells from anyone, scientists are near-giddy with excitement over the potential to model diseases in cell lines, as well as someday correct genetic mutations in people (see ARF news series). Bu
Sorting Out Parkinson’s: Exome Sequencing Points to Recycling Defect
RESEARCH NEWS 2011-07-26 Research News Sifting through the sequence of all the coding bits of the genome, two independent groups have identified a new mutation that causes Parkinson’s disease. The mutation sits in the gene for vacuolar protein sorting 35 (VPS35), altering its par
Slow Aβ; Clearance Is ApoE4’s Modus Operandi in Late-Onset AD
WEBINAR 2011-07-26 Alzforum has been pleased to partner with the journal Science Translational Medicine in hosting a Webinar discussion of a new Alzheimer’s disease research study published 29 June 2011. The journal generously granted free access to Castellano et al. for Al
Chinmoyee Maharana
India
Sheryl Grammer
United States
William Kadish
PAREXELUnited States
Jon Tinsley
Summit plc